SCHEMBL1176491

SCHEMBL1176491

Nc1cccc(C2CCCCC2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 1/20 0.53
HDAC4 P56524 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
BACE1 P56817 1/20 0.46
CYP11B2 P19099 1/20 0.46
CYP3A4 P08684 1/20 0.44
CASP1 P29466 1/20 0.44
RECQL P46063 1/20 0.44
DDB1 Q16531 1/20 0.44
CRBN Q96SW2 1/20 0.44
NPC1 O15118 1/20 0.40
ALDH1A1 P00352 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TDO2 P48775 1/20 0.40
ACMSD Q8TDX5 1/20 0.40
KDM4E B2RXH2 1/20 0.39
MAPT P10636 1/20 0.39
GFER P55789 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6100303 1.00 KMO (0.53) KMOHDAC4HDAC2HDAC8BACE1
SCHEMBL16334825 0.98 HDAC4 (0.52) KMOHDAC4HDAC2HDAC8BACE1
Hydrochloric Acid SCHEMBL4444055 0.96 HDAC4 (0.50) KMOHDAC4HDAC2HDAC8BACE1
SCHEMBL18956824 0.94 HDAC4 (0.47) KMOHDAC4HDAC2HDAC8BACE1
SCHEMBL273350 0.89 CYP3A4 (0.50) KMOHDAC4HDAC2HDAC8CYP3A4
SCHEMBL29411064 0.89 CYP3A4 (0.50) KMOHDAC4HDAC2HDAC8CYP3A4
Hydrochloric Acid SCHEMBL25305777 0.87 CYP3A4 (0.48) KMOHDAC4HDAC2HDAC8CYP3A4
SCHEMBL5667650 0.87 KMO (0.64) KMOHDAC4HDAC2HDAC8BACE1
SCHEMBL669730 0.87 KMO (0.64) KMOHDAC4HDAC2HDAC8BACE1
SCHEMBL5666805 0.84 KMO (0.62) KMOHDAC4HDAC2HDAC8BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120192449-A Maleimide high heat-resistant impact modifier and preparation method thereof 浙江烯苯醇新材料科技有限公司 2025-06-24 CN claimed
CN-114917727-B Hydrophobic eutectic solvent and preparation method and application thereof 苏州中科地星创新技术研究所有限公司 2023-05-16 CN claimed
CN-114917727-A Hydrophobic eutectic solvent and preparation method and application thereof 苏州中科地星创新技术研究所有限公司 2022-08-19 CN claimed
US-9690218-B2 Intermediate transfer member XEROX CORPORATION (US) 2017-06-27 US claimed
EP-2290452-B1 POSS melamine overcoated photoconductors XEROX CORP (US) 2016-06-01 EP claimed
US-8435632-B2 Intermediate transfer member XEROX CORPORATION (US) 2013-05-07 US claimed
US-8283398-B2 Polyhedral silsesquioxane modified polyimide containing intermediate transfer members XEROX CORPORATION (US) 2012-10-09 US claimed
US-20110223436-A1 INTERMEDIATE TRANSFER MEMBER XEROX CORPORATION (US) 2011-09-15 US claimed
US-20110223404-A1 INTERMEDIATE TRANSFER MEMBER XEROX CORPORATION (US) 2011-09-15 US claimed
US-20110053066-A1 POSS MELAMINE OVERCOATED PHOTOCONDUCTORS XEROX CORPORATION (US) 2011-03-03 US claimed
US-7897314-B1 Poss melamine overcoated photoconductors XEROX CORPORATION (US) 2011-03-01 US claimed
US-20110027598-A1 POLYHEDRAL SILSESQUIOXANE MODIFIED POLYIMIDE CONTAINING INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2011-02-03 US claimed
CN-117428187-B Method for preparing carbon-coated copper by in-situ reduction of polydopamine-like copper oxide, carbon-coated copper and application 深圳大学 2026-05-19 CN disclosed
EP-4722319-A2 COMPOSITION WITH ORGANIC MOLECULES Samsung Display Co., Ltd. (KR) 2026-04-08 EP disclosed
US-12595243-B2 Modulators of extracellular signal-regulated kinase GEN1E LIFESCIENCES INC. (US) 2026-04-07 US disclosed
EP-4077337-B1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2026-03-18 EP disclosed
US-4725616-A ANTIARTHRITIC AGENTS PFIZER INC. (US) 1988-02-16 US disclosed
EP-0208510-A2 1-Substituted oxindole-3-carboxamines as antiinflammatory and analgesic agents PFIZER INC. (US) 1987-01-14 EP disclosed
US-4616053-A Hydrophobic polyamides BAYER AKTIENGESELLSCHAFT (DE) 1986-10-07 US disclosed
US-3960868-A Derivatives of 6,7 or 8 cycloalkyl 4-oxo quinoline 3 carboxylic acid CIBA-GEIGY CORPORATION (US) 1976-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595243-B2 Modulators of extracellular signal-regulated kinase CDC42BPG, GRK3, ERBB2 KMO 3244/4885HDAC4 1861/4885HDAC2 1632/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.