Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21975301 | 0.98 | LMNA (0.64) | LMNABLMPTPN1ALOX15MEN1 | |
| SCHEMBL276587 | 0.95 | LMNA (0.59) | LMNABLMPTPN1ALOX15MEN1 | |
| SCHEMBL316430 | 0.95 | LMNA (0.59) | LMNABLMPTPN1ALOX15MEN1 | |
| SCHEMBL18092218 | 0.88 | LMNA (0.64) | LMNABLMPTPN1ALOX15MEN1 | |
| SCHEMBL10736358 | 0.87 | LMNA (0.46) | LMNABLMPTPN1ALOX15MEN1 | |
| SCHEMBL585190 | 0.86 | LMNA (0.59) | LMNABLMPTPN1ALOX15MEN1 | |
| SCHEMBL28922962 | 0.86 | LMNA (0.59) | LMNABLMPTPN1ALOX15MEN1 | |
| SCHEMBL2045830 | 0.86 | LMNA (0.48) | LMNABLMPTPN1ALOX15MEN1 | |
| SCHEMBL3408019 | 0.85 | HIF1A (0.45) | LMNABLMALOX15HIF1ATSHR | |
| SCHEMBL1784683 | 0.85 | LMNA (0.38) | LMNABLMALOX15HIF1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4021461-A | INSECTICIDES | ZOECON CORPORATION (US) | 1977-05-03 | — | — | US | disclosed |