SCHEMBL276587

SCHEMBL276587

CC(C)CCCC(C)CCC=O

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.59
BLM P54132 1/20 0.48
PTPN1 P18031 3/20 0.42
MEN1 O00255 1/20 0.42
CYP3A4 P08684 1/20 0.42
ALOX15 P16050 1/20 0.42
KMT2A Q03164 1/20 0.42
HIF1A Q16665 1/20 0.35
TSHR P16473 2/20 0.35
PTPN2 P17706 1/20 0.33
CDC25B P30305 1/20 0.33
ADH1B P00325 1/20 0.32
ADH1C P00326 1/20 0.32
ADH1A P07327 1/20 0.32
ALDH1A1 P00352 1/20 0.32
FNTA P49354 1/20 0.32
PGGT1B P53609 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL316430 1.00 LMNA (0.59) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL21975301 0.98 LMNA (0.64) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL11764950 0.95 LMNA (0.59) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL10736358 0.93 LMNA (0.46) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL28922962 0.91 LMNA (0.59) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL585190 0.91 LMNA (0.59) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL2045830 0.90 LMNA (0.48) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL18092218 0.88 LMNA (0.64) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL1784683 0.85 LMNA (0.38) LMNABLMALOX15HIF1ATSHR
SCHEMBL3408019 0.85 HIF1A (0.45) LMNABLMALOX15HIF1ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11844775-B2 Method of treating fatty acid oxidation disorders using Omega3/Omega6 unsaturated or branched chain fatty acids University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2023-12-19 US claimed
US-20210353581-A1 Method of Treating Fatty Acid Oxidation Disorders Using Omega3/Omega6 Unsaturated or Branched Chain Fatty Acids UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2021-11-18 US claimed
US-20210322357-A1 Method of Treating Fatty Acid Oxidation Disorders Using Omega3/Omega6 Unsaturated or Branched Chain Fatty Acids UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2021-10-21 US claimed
CN-117794504-A Iris root extract, compositions and methods for dermatological use 捷通国际有限公司 2024-03-29 CN disclosed
WO-2024030367-A2 FATTY ACID-D-AMINO ACID PEPTIDES CONJUGATES AS ANAPLEROTIC COMPOUNDS FOR USE IN TREATING PROPIONIC ACIDEMIA, METHYLMALONIC ACIDURIAS, AND ENERGY METABOLIC DISORDERS UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2024-02-08 WO disclosed
US-11844775-B2 Method of treating fatty acid oxidation disorders using Omega3/Omega6 unsaturated or branched chain fatty acids University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2023-12-19 US disclosed
WO-2023162653-A1 RESIST UNDERLAYER FILM FORMATION COMPOSITION 日産化学株式会社 2023-08-31 WO disclosed
CN-116113659-A Non-isocyanate polyurethane elastomer and composition containing the same 纳米技术有限责任公司(以生物科学博士名义) 2023-05-12 CN disclosed
CN-113348199-B Branched organosilicon compounds, methods of making branched organosilicon compounds, and copolymers formed therewith 美国陶氏有机硅公司 2023-02-17 CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
CN-114292171-A Method for preparing tetrahydrogeranyl ketone by catalytic rectification reduction of diketene 万华化学集团股份有限公司 2022-04-08 CN disclosed
EP-0583971-A1 Piperidine derivatives SANKYO COMPANY LIMITED (JP) 1994-02-23 EP disclosed
EP-0251827-B1 NEW CYCLIC ETHER DERIVATIVES, THEIR PREPARATION AND THEIR USE Sankyo Company Limited (JP) 1993-09-15 EP disclosed
EP-0536936-A1 Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use Sankyo Company Limited (JP) 1993-04-14 EP disclosed
CN-1059720-A Radicicol derivatives, its preparation method and anti-tumor activity thereof SANKYO CO (JP) 1992-03-25 CN disclosed
WO-1991018905-A1 RADICICOL DERIVATIVES, THEIR PREPARATION AND THEIR ANTI-TUMOR ACTIVITY SANKYO COMPANY LIMITED (JP) 1991-12-12 WO disclosed
EP-0437016-A2 Lipid A analogues having immunoactivating and anti-tumour activity Sankyo Company Limited (JP) 1991-07-17 EP disclosed
CN-1052481-A Lipoid category-A with immunocompetence and anti-tumor activity is like thing SANKYO CO (JP) 1991-06-26 CN disclosed
US-4891363-A PLATELET ACTIVATING FACTOR ANTAGONISTS SANKYO COMPANY LIMITED (JP) 1990-01-02 US disclosed
US-4021461-A INSECTICIDES ZOECON CORPORATION (US) 1977-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210353581-A1 Method of Treating Fatty Acid Oxidation Disorders Using Omega3/Omega6 Unsaturated or Branched Chain Fatty Acids ELOVL6, ELOVL3, CPT1B LMNA 2477/4885BLM 3348/4885PTPN1 4604/4885
US-11844775-B2 Method of treating fatty acid oxidation disorders using Omega3/Omega6 unsaturated or branched chain fatty acids ELOVL6, ELOVL3, CPT1B LMNA 2551/4885BLM 3418/4885PTPN1 4636/4885
US-20210322357-A1 Method of Treating Fatty Acid Oxidation Disorders Using Omega3/Omega6 Unsaturated or Branched Chain Fatty Acids ELOVL6, ELOVL3, CPT1B LMNA 2551/4885BLM 3418/4885PTPN1 4636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.