Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.30 |
| ▸ | KDM4A | O75164 | 1/20 | 0.30 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11765146 | 1.00 | LMNA (0.46) | LMNABLMPTPN1ALOX15MEN1 | |
| SCHEMBL11762290 | 0.96 | BLM (0.48) | LMNABLMPTPN1ALOX15MEN1 | |
| SCHEMBL11762287 | 0.96 | BLM (0.48) | LMNABLMPTPN1ALOX15MEN1 | |
| SCHEMBL24479774 | 0.86 | ALDH1A1 (0.46) | LMNABLMPTPN1ALDH1A1KDM1A | |
| SCHEMBL28599123 | 0.84 | ALDH1A1 (0.40) | BLMPTPN1ALDH1A1KDM1AMAPT | |
| SCHEMBL1783404 | 0.84 | PPARG (0.36) | ALDH1A1KDM1AMAPTPPARGPPARD | |
| SCHEMBL1783406 | 0.84 | PPARG (0.36) | ALDH1A1KDM1AMAPTPPARGPPARD | |
| SCHEMBL11765706 | 0.82 | PPARG (0.36) | LMNABLMALOX15MEN1CYP3A4 | |
| SCHEMBL11765710 | 0.82 | PPARG (0.36) | LMNABLMALOX15MEN1CYP3A4 | |
| SCHEMBL11764066 | 0.82 | KDM1A (0.48) | LMNABLMPTPN1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4021461-A | INSECTICIDES | ZOECON CORPORATION (US) | 1977-05-03 | — | — | US | disclosed |