Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12491843 | 0.84 | LMNA (0.58) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL9340896 | 0.83 | LMNA (0.62) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL16848409 | 0.82 | LMNA (0.59) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL12490841 | 0.82 | LMNA (0.59) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL12491658 | 0.82 | LMNA (0.59) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL12491784 | 0.82 | LMNA (0.59) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL12491146 | 0.82 | LMNA (0.59) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL12491875 | 0.82 | LMNA (0.59) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL12491599 | 0.82 | LMNA (0.59) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL341791 | 0.81 | LMNA (0.60) | LMNACYP2D6SPHK1GMNNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042619-A | Derivatives of carboxy-terminated polybutadienes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-08-16 | — | — | US | disclosed |