Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16074709 | 0.90 | LMNA (0.70) | LMNATSHRTHRBCYP2D6SPHK1 | |
| SCHEMBL8757790 | 0.90 | LMNA (0.76) | LMNATSHRCYP2D6SPHK1GMNN | |
| SCHEMBL14763967 | 0.86 | LMNA (0.52) | LMNATSHRTHRBCYP2D6SPHK1 | |
| SCHEMBL3921436 | 0.85 | LMNA (0.62) | LMNATSHRTHRBCYP2D6SPHK1 | |
| SCHEMBL18961175 | 0.84 | LMNA (0.61) | LMNATSHRCYP2D6SPHK1GMNN | |
| SCHEMBL13757121 | 0.84 | LMNA (0.61) | LMNATSHRCYP2D6SPHK1GMNN | |
| SCHEMBL6548253 | 0.84 | LMNA (0.46) | LMNATHRBALDH1A1TDP1 | |
| SCHEMBL11765327 | 0.83 | LMNA (0.50) | LMNATHRBCYP2D6SPHK1GMNN | |
| SCHEMBL341791 | 0.83 | LMNA (0.60) | LMNATSHRCYP2D6SPHK1GMNN | |
| SCHEMBL7644910 | 0.82 | LMNA (0.73) | LMNATSHRTHRBCYP2D6SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110431217-A | Fuel additive for improving octane number, preparation method and application thereof | SABIC GLOBAL TECHNOLOGIES BV | 2019-11-08 | — | — | CN | disclosed |
| EP-0603469-A1 | Alkylpolyol ethers as cosolvents for ink jet inks | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-06-29 | — | — | EP | disclosed |
| US-5268027-A | Water soluble | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-12-07 | — | — | US | disclosed |