Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11571053 | 0.93 | KDM1A (0.47) | KDM1AMAOAMAOBRCOR1 | |
| SCHEMBL11572399 | 0.80 | OPRL1 (0.52) | KDM1AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL11569798 | 0.78 | OPRL1 (0.50) | KDM1AMAOAMAOB | |
| SCHEMBL29218852 | 0.74 | KDM1A (0.47) | KDM1AMAOAMAOBSLC6A3SLC6A4 | |
| SCHEMBL11761702 | 0.72 | OPRL1 (0.50) | KDM1AMAOAMAOBSLC6A4 | |
| SCHEMBL9735920 | 0.71 | CCNB2 (0.47) | KDM1AMAOAMAOBSLC6A3SLC6A4 | |
| SCHEMBL11767328 | 0.68 | KDM1A (0.41) | KDM1AMAOAMAOBSLC6A3SLC6A4 | |
| SCHEMBL11765784 | 0.68 | KDM1A (0.41) | KDM1ASLC6A3SLC6A4SLC6A2RCOR1 | |
| SCHEMBL5089578 | 0.68 | TET3 (0.51) | MAOAMAOB | |
| SCHEMBL4004257 | 0.68 | TET3 (0.51) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053637-A | ANTIDEPRESSANTS | ASTRA LAKEMEDAL AKTIEBOLAG (SW) | 1977-10-11 | — | — | US | disclosed |