Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11763463 | 0.91 | MAPK1 (0.44) | KDM1AMAPK1SMN1; SMN2ALOX15SLC6A4 | |
| SCHEMBL11571053 | 0.76 | KDM1A (0.47) | KDM1ARCOR1MAPK1SMN1; SMN2HSD11B1 | |
| SCHEMBL11767328 | 0.76 | KDM1A (0.41) | KDM1ARCOR1MAPK1SMN1; SMN2HSD11B1 | |
| SCHEMBL8992298 | 0.73 | OPRM1 (0.41) | KDM1AMAPK1SMN1; SMN2ALOX15 | |
| SCHEMBL11765485 | 0.68 | KDM1A (0.50) | KDM1ARCOR1SLC6A3SLC6A2SLC6A4 | |
| Ethylbenzene SCHEMBL11073829 | 0.67 | OPRL1 (0.44) | KDM1ASLC6A4 | |
| SCHEMBL11762923 | 0.67 | HTR2C (0.51) | MAPK1SMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL9586032 | 0.67 | ALOX15 (0.40) | MAPK1SMN1; SMN2ALOX15HSD11B1 | |
| SCHEMBL2019808 | 0.66 | MAPK1 (0.46) | MAPK1SMN1; SMN2 | |
| SCHEMBL23699058 | 0.66 | OPRL1 (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053637-A | ANTIDEPRESSANTS | ASTRA LAKEMEDAL AKTIEBOLAG (SW) | 1977-10-11 | — | — | US | disclosed |