Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | ESRRA | P11474 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1835529 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPK1LMNAMEN1KMT2A | |
| SCHEMBL1954199 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPK1LMNAKMT2APOLB | |
| SCHEMBL1834514 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MAPK1LMNAPOLBFAAH | |
| SCHEMBL1952405 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPK1LMNAMEN1KMT2A | |
| SCHEMBL1839851 | 0.80 | ALDH1A1 (0.44) | ALDH1A1MAPK1LMNAMEN1KMT2A | |
| SCHEMBL1837122 | 0.79 | KDM4E (0.59) | ALDH1A1MAPK1GAAROCK2LMNA | |
| SCHEMBL9230576 | 0.79 | ALDH1A1 (0.66) | ALDH1A1MAPK1PGRGAAPTGS1 | |
| SCHEMBL989117 | 0.78 | ALDH1A1 (0.60) | ALDH1A1MAPK1GAAHPGDLMNA | |
| SCHEMBL1021748 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPK1LMNAMEN1KMT2A | |
| SCHEMBL1951250 | 0.78 | ALDH1A1 (0.46) | ALDH1A1MAPK1LMNAFAAHCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962302-A | Production of isocyanates from esters of carbamic acids (urethanes) | ATLANTIC RICHFIELD COMPANY (US) | 1976-06-08 | — | — | US | claimed |
| US-3962302-A | Production of isocyanates from esters of carbamic acids (urethanes) | ATLANTIC RICHFIELD COMPANY (US) | 1976-06-08 | — | — | US | disclosed |