SCHEMBL989117

SCHEMBL989117

Cc1ccc(NC(=O)Oc2ccccc2)cc1NC(=O)Oc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.60
MAPT P10636 5/20 0.60
CYP1A2 P05177 1/20 0.58
KDM4E B2RXH2 3/20 0.57
POLB P06746 1/20 0.57
KMT2A Q03164 3/20 0.56
MEN1 O00255 2/20 0.56
THRB P10828 1/20 0.56
GFER P55789 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
RAD51 Q06609 2/20 0.55
GAA P10253 3/20 0.55
LMNA P02545 2/20 0.55
TP53 P04637 1/20 0.55
MAPK1 P28482 2/20 0.54
FAAH O00519 1/20 0.54
CYP3A4 P08684 1/20 0.54
HTT P42858 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
GLA P06280 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15374817 0.96 ALDH1A1 (0.60) ALDH1A1MAPTCYP1A2KDM4EPOLB
SCHEMBL13859992 0.94 ALDH1A1 (0.55) ALDH1A1MAPTCYP1A2KDM4EPOLB
SCHEMBL13104381 0.94 MAPT (0.54) ALDH1A1MAPTCYP1A2KDM4EPOLB
SCHEMBL13593024 0.94 MAPT (0.57) ALDH1A1MAPTCYP1A2KDM4EPOLB
SCHEMBL799499 0.93 ALDH1A1 (0.54) ALDH1A1MAPTCYP1A2KDM4EPOLB
SCHEMBL13104382 0.92 MAPT (0.52) ALDH1A1MAPTCYP1A2KDM4EPOLB
SCHEMBL25342944 0.92 ALDH1A1 (0.51) ALDH1A1MAPTCYP1A2KDM4EPOLB
SCHEMBL13104406 0.92 MAPT (0.58) ALDH1A1MAPTCYP1A2KDM4EPOLB
SCHEMBL13104359 0.92 MAPT (0.55) ALDH1A1MAPTCYP1A2KDM4EPOLB
SCHEMBL1952563 0.92 PORCN (0.60) ALDH1A1MAPTCYP1A2KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3962302-A Production of isocyanates from esters of carbamic acids (urethanes) ATLANTIC RICHFIELD COMPANY (US) 1976-06-08 US claimed
JP-61254548-A None JP disclosed
WO-2023080257-A1 METHOD FOR PRODUCING ISOCYANATE COMPOUNDS, METHOD FOR PRODUCING CARBAMATE COMPOUNDS, METHOD FOR RECOVERING AMINE COMPOUNDS, AND ISOCYANATE COMPOSITION 旭化成株式会社 2023-05-11 WO disclosed
US-20230021574-A1 METHOD FOR PRODUCING ISOCYANATE ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-01-26 US disclosed
US-11352319-B2 Method for producing carbamate and method for producing isocyanate ASAHI KASEI KABUSHIKI KAISHA (JP) 2022-06-07 US disclosed
CN-110546135-B Method for producing isocyanate 旭化成株式会社 2021-12-14 CN disclosed
US-11192853-B2 Separation method and method for producing isocyanate ASAHI KASEI CHEMICALS CORPORATION (JP) 2021-12-07 US disclosed
EP-3293173-B1 METHOD FOR PRODUCING ISOCYANATE ASAHI CHEMICAL IND (JP) 2021-07-28 EP disclosed
EP-3838892-A1 METHOD FOR PRODUCING ISOCYANATE Asahi Kasei Kabushiki Kaisha (JP) 2021-06-23 EP disclosed
US-20210179548-A1 METHOD FOR PRODUCING CARBAMATE AND METHOD FOR PRODUCING ISOCYANATE ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-06-17 US disclosed
US-20100105941-A1 NOVEL COMPOUND FOR COLOR-PRODUCING COMPOSITION, AND RECORDING MATERIAL KABASHIMA KAZUO 2010-04-29 US disclosed
US-20100105941-A1 NOVEL COMPOUND FOR COLOR-PRODUCING COMPOSITION, AND RECORDING MATERIAL KABASHIMA KAZUO 2010-04-29 US disclosed
US-7635662-B2 Compound for color-producing composition, and recording material CHEMIPRO KASEI KAISHA, LTD. (JP) 2009-12-22 US disclosed
US-7635662-B2 Compound for color-producing composition, and recording material CHEMIPRO KASEI KAISHA, LTD. (JP) 2009-12-22 US disclosed
JP-S61254548-A METHOD FOR CONCENTRATING DIPHENYL TOLYLENEDICARBAMATE SOLUTION MITSUI TOATSU CHEM INC 1986-11-12 JP disclosed
US-4453973-A 3-(CARBAMOYLOXY)-ANILIDES SCHERING AKTIENGESELLSCHAFT (DE) 1984-06-12 US disclosed
US-4453966-A HERBICIDES SCHERING AKTIENGESELLSCHAFT (DE) 1984-06-12 US disclosed
US-4426222-A Carbaminic acid esters with herbicidal properties SCHERING AKTIENGESELLSCHAFT (DE) 1984-01-17 US disclosed
US-3993685-A Process for the production of urethanes ATLANTIC RICHFIELD COMPANY (US) 1976-11-23 US disclosed
US-3962302-A Production of isocyanates from esters of carbamic acids (urethanes) ATLANTIC RICHFIELD COMPANY (US) 1976-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11352319-B2 Method for producing carbamate and method for producing isocyanate CPS1, CA7, CA4 ALDH1A1 781/4885MAPT 691/4885CYP1A2 502/4885
US-20210179548-A1 METHOD FOR PRODUCING CARBAMATE AND METHOD FOR PRODUCING ISOCYANATE CPS1, CA7, CA4 ALDH1A1 781/4885MAPT 691/4885CYP1A2 502/4885
US-20230021574-A1 METHOD FOR PRODUCING ISOCYANATE CPS1, IDH3A, ALKBH3 ALDH1A1 1551/4885MAPT 1942/4885CYP1A2 160/4885
US-11192853-B2 Separation method and method for producing isocyanate IDH3A, IDH3B, CA9 ALDH1A1 278/4885MAPT 3211/4885CYP1A2 527/4885
US-20100105941-A1 NOVEL COMPOUND FOR COLOR-PRODUCING COMPOSITION, AND RECORDING MATERIAL UMPS, UROD, UGP2 ALDH1A1 147/4885MAPT 747/4885CYP1A2 451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.