SCHEMBL11765622

SCHEMBL11765622

CCCCCC(=O)c1ccccc1F

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.54
HDAC1 Q13547 1/20 0.54
HDAC2 Q92769 1/20 0.54
CTNNB1 P35222 2/20 0.51
WNT3A P56704 2/20 0.51
HTT P42858 2/20 0.50
PTPN1 P18031 1/20 0.50
ERCC5 P28715 1/20 0.50
FEN1 P39748 1/20 0.50
ALDH1A1 P00352 2/20 0.49
KDM4E B2RXH2 1/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
MAPT P10636 1/20 0.49
ATM Q13315 1/20 0.49
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
HSD17B3 P37058 6/20 0.47
HTR7 P34969 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28223126 0.98 HDAC3 (0.53) HDAC3HDAC1HDAC2CTNNB1WNT3A
SCHEMBL10594894 0.98 HDAC3 (0.53) HDAC3HDAC1HDAC2CTNNB1WNT3A
SCHEMBL6757360 0.95 HDAC3 (0.55) HDAC3HDAC1HDAC2CTNNB1WNT3A
SCHEMBL14732971 0.89 CTNNB1 (0.61) CTNNB1WNT3APTPN1ERCC5FEN1
SCHEMBL3121320 0.87 ALDH1A1 (0.57) HDAC3HDAC1HDAC2CTNNB1WNT3A
SCHEMBL18936367 0.85 CTNNB1 (0.49) HDAC3HDAC1HDAC2CTNNB1WNT3A
Alcohol SCHEMBL3646461 0.84 ALDH1A1 (0.54) HDAC3HDAC1HDAC2CTNNB1WNT3A
SCHEMBL30089515 0.82 CTNNB1 (0.68) CTNNB1WNT3APTPN1ERCC5FEN1
SCHEMBL18936230 0.82 CTNNB1 (0.49) HDAC3HDAC1HDAC2CTNNB1WNT3A
SCHEMBL28620969 0.82 CTNNB1 (0.51) CTNNB1WNT3APTPN1ERCC5FEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4064132-A ANTIINFLAMMATORY AGENTS JANSSEN PHARMACEUTICA N.V. (BE) 1977-12-20 US disclosed
US-4060528-A ANTIINFLAMMATORY JANSSEN PHARMACEUTICA N.V. (BE) 1977-11-29 US disclosed
US-4035376-A ESTERS, AMIDES, HYDROXAMIC ACIDS, ANTIINFLAMMATORY JANSSEN PHARMACEUTICA N.V. (BE) 1977-07-12 US disclosed