⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1505731 | 0.70 | — | — | |
| SCHEMBL11833798 | 0.70 | — | — | |
| SCHEMBL7086935 | 0.70 | — | — | |
| SCHEMBL64656 | 0.67 | — | — | |
| SCHEMBL9175735 | 0.67 | — | — | |
| Guanidine SCHEMBL165720 | 0.65 | NOS2 (0.42) | — | |
| Guanidine SCHEMBL2003 | 0.65 | — | — | |
| Guanidine SCHEMBL5613752 | 0.65 | — | — | |
| Guanidine SCHEMBL11330173 | 0.65 | — | — | |
| SCHEMBL6195802 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4024128-A | HYPOGLYCEMIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1977-05-17 | — | — | US | disclosed |