Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL165720 | 1.00 | NOS2 (0.42) | — | |
| Guanidine SCHEMBL29983942 | 1.00 | — | — | |
| Guanidine SCHEMBL5613752 | 1.00 | — | — | |
| Guanidine SCHEMBL11330173 | 1.00 | — | — | |
| Guanidine SCHEMBL25310528 | 0.93 | — | — | |
| Guanidine SCHEMBL66976 | 0.93 | — | — | |
| Guanidine SCHEMBL3349156 | 0.93 | — | — | |
| Guanidine SCHEMBL17981827 | 0.93 | — | — | |
| Guanidine SCHEMBL3310493 | 0.93 | — | — | |
| Guanidine SCHEMBL6274847 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 359024 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213310-A9 | CARBON CHAIN SUBSTANCE FOR REGULATING TRANSMEMBRANE TRANSPORT AND FLUIDITY OF CELL MEMBRANES, AND PREPARATION AND USE THEREOF | 太阳雨林(北京)生物医药有限公司 | 2025-02-20 | — | — | WO | claimed |
| CN-117625593-B | Blood sample DNA extraction kit and nucleic acid extraction method | 广东明志医学检验实验室有限公司 | 2025-01-07 | — | — | CN | claimed |
| CN-119223702-A | Sample treatment fluid and troponin complex detection kit and application | 深圳市卓润生物科技有限公司 | 2024-12-31 | — | — | CN | claimed |
| CN-114698379-B | Protein purification using a split intein system | 思拓凡生物工艺研发有限公司 | 2024-12-27 | — | — | CN | claimed |
| CN-118558156-B | Functionalized nanofiber hemodialysis membrane, preparation method, application and matched equipment | 吉林大学 | 2024-12-27 | — | — | CN | claimed |
| CN-119213086-A | Coating agent for forming large-area perovskite thin film and method for forming large-area perovskite thin film using same | 韩华思路信 | 2024-12-27 | — | — | CN | claimed |
| CN-119193770-A | Nucleic acid processing reagent, detection kit, microfluidic system, detection method and application of detection method | 安邦(新疆)生物科技有限公司 | 2024-12-27 | — | — | CN | claimed |
| US-20240425465-A1 | PYRIDAZINEDIONE-BASED HETEROBICYCLIC COVALENT LINKERS AND METHODS AND APPLICATIONS THEREOF | SYNTABIO LLC | 2024-12-26 | — | — | US | claimed |
| US-12173430-B2 | Process for producing carbon fibers and carbon fibers made therefrom | CYTEC INDUSTRIES INC. (US) | 2024-12-24 | — | — | US | claimed |
| CN-119162165-A | One-tube plant DNA rapid extraction reagent, use method and application thereof | 江苏省农业科学院 | 2024-12-20 | — | — | CN | claimed |
| US-3952057-A | Process for the preparation of guanidine carbonate | CHEMIE LINZ AG (OE) | 1976-04-20 | — | — | US | claimed |
| US-3947396-A | Coacervation of anion-containing aqueous disperse systems with amphoteric polyelectrolytes | THE DOW CHEMICAL COMPANY (US) | 1976-03-30 | — | — | US | claimed |
| US-3947455-A | VASCONSTRICTORS | ARMOUR PHARMACEUTICAL COMPANY (US) | 1976-03-30 | — | — | US | claimed |
| US-3944586-A | Preparation of salts of antimony (V) esters | KNOWLES RICHARD NORRIS | 1976-03-16 | — | — | US | claimed |
| US-3943954-A | Pipeline transportation of viscous hydrocarbons | TEXACO INC. (US) | 1976-03-16 | — | — | US | claimed |
| US-3941825-A | ANTIPROTOZOA INTERMEDIATES | AMERICAN CYANAMID COMPANY (US) | 1976-03-02 | — | — | US | claimed |
| US-3940298-A | Thermal laser pumped with high nitrogen content propellants | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1976-02-24 | — | — | US | claimed |
| US-3936560-A | Self-sealable corrosion protectable packaging material and method of making | THE ORCHARD CORPORATION OF AMERICA (US) | 1976-02-03 | — | — | US | claimed |
| US-3936562-A | Fire retardant fabrics | UNITED MERCHANTS AND MANUFACTURERS, INC. (US) | 1976-02-03 | — | — | US | claimed |
| US-3931552-A | Capacitor electrolyte | P. R. MALLORY & CO., INC. (US) | 1976-01-06 | — | — | US | claimed |