Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11701351 | 0.95 | ALDH1A1 (0.53) | MAPTPLA2G1BATG4BADRB2ADRB1 | |
| SCHEMBL5166149 | 0.92 | TSHR (0.56) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL11699178 | 0.89 | CA1 (0.57) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL11702063 | 0.88 | CA12 (0.56) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL17565214 | 0.87 | MAPT (0.51) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL11702741 | 0.86 | ALDH1A1 (0.59) | MAPTPLA2G1BATG4BADRB2ADRB1 | |
| SCHEMBL110051 | 0.84 | ALDH1A1 (0.64) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL27667934 | 0.82 | ALDH1A1 (0.62) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL27668055 | 0.82 | ALDH1A1 (0.62) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL27668352 | 0.82 | ALDH1A1 (0.62) | MAPTCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4043976-A | N,N'-DIBENZOYLHYDRAZINE DERIVATIVE | UBE INDUSTRIES, LTD. (JA) | 1977-08-23 | — | — | US | disclosed |