Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 8/20 | 0.54 |
| ▸ | TRPM2 | O94759 | 3/20 | 0.54 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.54 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.53 |
| ▸ | ATG4B | Q9Y4P1 | 7/20 | 0.51 |
| ▸ | THRA | P10827 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11766309 | 1.00 | PLA2G1B (0.54) | PLA2G1BTRPM2CYSLTR2CYSLTR1TRPA1 | |
| SCHEMBL6942264 | 0.98 | THRA (0.54) | PLA2G1BTRPM2CYSLTR2CYSLTR1TRPA1 | |
| SCHEMBL11765624 | 0.98 | THRA (0.54) | PLA2G1BTRPM2CYSLTR2CYSLTR1TRPA1 | |
| SCHEMBL11765630 | 0.98 | THRA (0.54) | PLA2G1BTRPM2CYSLTR2CYSLTR1TRPA1 | |
| SCHEMBL6942269 | 0.98 | THRA (0.54) | PLA2G1BTRPM2CYSLTR2CYSLTR1TRPA1 | |
| SCHEMBL11760926 | 0.98 | THRA (0.54) | PLA2G1BTRPM2CYSLTR2CYSLTR1TRPA1 | |
| SCHEMBL11760921 | 0.98 | THRA (0.54) | PLA2G1BTRPM2CYSLTR2CYSLTR1TRPA1 | |
| SCHEMBL11763066 | 0.95 | ALDH1A1 (0.50) | PLA2G1BTRPM2CYSLTR2CYSLTR1TRPA1 | |
| SCHEMBL11763060 | 0.95 | ALDH1A1 (0.50) | PLA2G1BTRPM2CYSLTR2CYSLTR1TRPA1 | |
| SCHEMBL11768167 | 0.88 | ALDH1A1 (0.50) | PLA2G1BTRPM2CYSLTR2CYSLTR1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061587-A | Liquid crystalline cinnamic acid esters | HOFFMANN-LA ROCHE INC. (US) | 1977-12-06 | — | — | US | disclosed |