Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11761103 | 0.92 | MEN1 (0.42) | MEN1KMT2ANPSR1NPC1MAPT | |
| SCHEMBL11765414 | 0.85 | MEN1 (0.39) | MEN1KMT2ACHRM2CHRM1CHRM3 | |
| SCHEMBL28056873 | 0.71 | MAPT (0.52) | MEN1KMT2ACHRM2CHRM1CHRM3 | |
| SCHEMBL11764844 | 0.71 | RAB9A (0.40) | MEN1KMT2ANPSR1NPC1MAPT | |
| SCHEMBL26985642 | 0.70 | ALDH1A1 (0.37) | NPC1RAB9ALMNA | |
| SCHEMBL7844145 | 0.68 | MEN1 (0.55) | MEN1KMT2AKCNH2NPSR1NPC1 | |
| SCHEMBL9068394 | 0.67 | IDO1 (0.62) | MEN1KMT2AKCNH2NPSR1TSHR | |
| SCHEMBL26985674 | 0.65 | ALDH1A1 (0.44) | MEN1KMT2AKCNH2NPSR1MAPT | |
| SCHEMBL3422695 | 0.63 | SLC2A1 (0.58) | MEN1KMT2ACHRM2CHRM1CHRM3 | |
| SCHEMBL10941418 | 0.63 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4005197-A | Combating insects, acarids and nematodes with S-alkoxyethyl-phenyl-di- and tri-thiophosphonic acid esters | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-25 | — | — | US | disclosed |