SCHEMBL1176702

SCHEMBL1176702

Cc1ccc(O)c(Cc2ccc(O)c(C)c2)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.68
ESR2 Q92731 2/20 0.68
AMY1A P0DUB6 1/20 0.59
TP53 P04637 2/20 0.57
TDP1 Q9NUW8 1/20 0.57
MAPT P10636 2/20 0.48
TRPA1 O75762 1/20 0.43
THRA P10827 1/20 0.42
THRB P10828 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
HTT P42858 1/20 0.41
SNCA P37840 2/20 0.41
ALOX15 P16050 4/20 0.41
IGF1R P08069 1/20 0.41
AR P10275 1/20 0.40
HSD17B10 Q99714 3/20 0.40
MEN1 O00255 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30485785 1.00 ESR1 (0.68) ESR1ESR2AMY1ATP53TDP1
SCHEMBL31294095 0.88 AMY1A (0.68) ESR1ESR2AMY1ATP53TDP1
SCHEMBL24541912 0.86 AMY1A (0.61) ESR1ESR2AMY1ATP53TDP1
SCHEMBL15721690 0.85 AMY1A (0.59) ESR1ESR2AMY1ATP53TDP1
SCHEMBL5364380 0.85 AMY1A (0.65) ESR1ESR2AMY1ATP53TDP1
SCHEMBL30764682 0.85 AMY1A (0.65) ESR1ESR2AMY1ATP53TDP1
SCHEMBL29636485 0.85 ESR1 (0.68) ESR1ESR2AMY1ATP53TDP1
SCHEMBL3188653 0.85 ESR1 (0.68) ESR1ESR2AMY1ATP53TDP1
SCHEMBL8052862 0.85 ESR1 (0.73) ESR1ESR2AMY1ATP53TDP1
SCHEMBL21294094 0.84 AMY1A (0.58) ESR1ESR2AMY1ATP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2677003-B1 POLYCARBONATE RESIN COMPOSITION MITSUBISHI CHEM CORP (JP) 2023-09-27 EP disclosed
US-20230039679-A1 COMPOUNDS FOR INHIBITING TNIK AND MEDICAL USES THEREOF INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2023-02-09 US disclosed
EP-3318603-B1 POLYCARBONATE RESIN COMPOSITION, METHOD FOR PRODUCING SAME, AND MOLDED OBJECT MITSUBISHI CHEM CORP (JP) 2020-11-18 EP disclosed
EP-3318603-A1 POLYCARBONATE RESIN COMPOSITION, METHOD FOR PRODUCING SAME, AND MOLDED OBJECT Mitsubishi Chemical Corporation (JP) 2018-05-09 EP disclosed
US-20180118883-A1 POLYCARBONATE RESIN COMPOSITION, METHOD FOR PRODUCING SAME, AND MOLDED OBJECT MITSUBISHI CHEMICAL CORPORATION (JP) 2018-05-03 US disclosed
EP-2511339-B1 POLYCARBONATE RESIN COMPOSITION AND MOLDED BODY, FILM, PLATE AND INJECTION-MOLDED ARTICLE OBTAINED BY MOLDING SAME MITSUBISHI CHEM CORP (JP) 2017-06-07 EP disclosed
EP-2881771-A1 POLYCARBONATE RESIN COMPOSITION AND TRANSPARENT FILM Mitsubishi Chemical Corporation (JP) 2015-06-10 EP disclosed
US-20150141577-A1 POLYCARBONATE RESIN AND TRANSPARENT FILM COMPRISING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2015-05-21 US disclosed
US-8742057-B2 Polycarbonate resin composition MITSUBISHI CHEMICAL CORPORATION (JP) 2014-06-03 US disclosed
EP-2677003-A1 POLYCARBONATE RESIN COMPOSITION Mitsubishi Chemical Corporation (JP) 2013-12-25 EP disclosed
US-7217483-B2 Electrophotographic photoreceptor, drum cartridge employing the electrophotographic photoreceptor, and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2007-05-15 US disclosed
US-20060134541-A1 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2006-06-22 US disclosed
US-20060068310-A1 Electrophotographic photoreceptor, drum cartridge employing the electrophotographic photoreceptor, and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION, TOKYO, JAPAN 2006-03-30 US disclosed
EP-1571495-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND, INCLUDING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR, DRUM CARTRIDGE AND IMAGE FORMING APPARATUS Mitsubishi Chemical Corporation (JP) 2005-09-07 EP disclosed
EP-1569038-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR Mitsubishi Chemical Corporation (JP) 2005-08-31 EP disclosed
US-6884556-B2 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2005-04-26 US disclosed
CN-1118003-C Photoresist scavenger composition TONGJIN CHEMICALS INDUSTRY CO (KR) 2003-08-13 CN disclosed
US-20030087173-A1 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2003-05-08 US disclosed
EP-1286224-A1 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2003-02-26 EP disclosed
CN-1258730-A Photoresist scavenger composition TONGJIN CHEMICALS INDUSTRY CO (KR) 2000-07-05 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230039679-A1 COMPOUNDS FOR INHIBITING TNIK AND MEDICAL USES THEREOF TNNI3K, TNK1, TNIK ESR1 3186/4885ESR2 2501/4885AMY1A 4600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.