SCHEMBL30764682

SCHEMBL30764682

Cc1ccc(O)c(Cc2cc(C)c(O)c(C)c2)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 1/20 0.65
SHBG P04278 1/20 0.47
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
TP53 P04637 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
TRPA1 O75762 1/20 0.43
ALK Q9UM73 1/20 0.42
HTT P42858 1/20 0.41
PTGS1 P23219 3/20 0.41
PTGS2 P35354 3/20 0.41
HMGB1 P09429 1/20 0.41
CXCL12 P48061 1/20 0.41
MAPT P10636 2/20 0.40
ALOX15 P16050 3/20 0.40
HSD17B10 Q99714 3/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
HPGD P15428 2/20 0.40
CYP3A4 P08684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5364380 1.00 AMY1A (0.65) AMY1ASHBGESR1ESR2TP53
SCHEMBL15721690 0.89 AMY1A (0.59) AMY1ASHBGESR1ESR2TP53
SCHEMBL4056593 0.89 AMY1A (0.75) AMY1ASHBGESR1ESR2TP53
SCHEMBL210867 0.89 SHBG (0.67) AMY1ASHBGESR1ESR2TP53
SCHEMBL2386946 0.88 AMY1A (0.69) AMY1ASHBGESR1ESR2TP53
SCHEMBL30320337 0.88 AMY1A (0.69) AMY1ASHBGESR1ESR2TP53
SCHEMBL21294094 0.87 AMY1A (0.58) AMY1ASHBGESR1ESR2TP53
SCHEMBL21096825 0.86 AMY1A (0.66) AMY1ASHBGESR1ESR2TP53
SCHEMBL1176702 0.85 ESR1 (0.68) AMY1AESR1ESR2TP53TDP1
SCHEMBL30485785 0.85 ESR1 (0.68) AMY1AESR1ESR2TP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4306571-A1 POLYPHENYLENE ETHER, METHOD FOR PRODUCING SAME, THERMALLY CURABLE COMPOSITION, PREPREG, AND MULTILAYER BODY Asahi Kasei Kabushiki Kaisha (JP) 2024-01-17 EP disclosed