Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 3/20 | 0.45 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.44 |
| ▸ | ACSL6 | Q9UKU0 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11772100 | 0.94 | LTB4R (0.49) | LTB4RTP53TTRACSL1ACSL6 | |
| SCHEMBL11493899 | 0.91 | TTR (0.47) | LTB4RTP53PTPN11TTRACSL1 | |
| SCHEMBL11767090 | 0.91 | LTB4R (0.58) | LTB4RTP53PLA2G2ATSHRPLA2G4B | |
| SCHEMBL11767853 | 0.90 | TTR (0.49) | LTB4RTP53TTRACSL1ACSL6 | |
| SCHEMBL11767439 | 0.86 | TTR (0.50) | LTB4RTP53TTRKDM4EMEN1 | |
| SCHEMBL11486616 | 0.86 | LTB4R (0.50) | LTB4RTP53PTPN11TTRACSL1 | |
| SCHEMBL11768290 | 0.85 | LTB4R (0.63) | LTB4RTP53PLA2G2ATSHRPLA2G4B | |
| SCHEMBL11767401 | 0.85 | LTB4R (0.58) | LTB4RTP53PLA2G2ATSHRPLA2G4B | |
| SCHEMBL11785980 | 0.85 | LTB4R (0.56) | LTB4RTP53PLA2G2ATSHRPLA2G4B | |
| SCHEMBL11769279 | 0.85 | LTB4R (0.53) | LTB4RTTRRARBMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3989721-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-11-02 | — | — | US | disclosed |
| US-3989720-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-11-02 | — | — | US | disclosed |
| US-3988352-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-10-26 | — | — | US | disclosed |
| US-3979414-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-09-07 | — | — | US | disclosed |
| US-3965115-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-06-22 | — | — | US | disclosed |
| US-3963753-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-06-15 | — | — | US | disclosed |
| US-3963752-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-06-15 | — | — | US | disclosed |