Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.53 |
| ▸ | TTR | P02766 | 4/20 | 0.47 |
| ▸ | RARB | P10826 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11766732 | 0.92 | TTR (0.50) | LTB4RTTRMEN1ALDH1A1KMT2A | |
| SCHEMBL11769175 | 0.91 | LTB4R (0.54) | LTB4RTTRRARBMEN1ALDH1A1 | |
| SCHEMBL11767363 | 0.87 | TTR (0.52) | LTB4RTTRMEN1ALDH1A1KMT2A | |
| SCHEMBL11769758 | 0.86 | LTB4R (0.56) | LTB4RTTRRARBMEN1ALDH1A1 | |
| SCHEMBL11771256 | 0.85 | LTB4R (0.54) | LTB4RTTRRARBMEN1ALDH1A1 | |
| SCHEMBL11811339 | 0.85 | LTB4R (0.54) | LTB4RTTRRARBMEN1ALDH1A1 | |
| SCHEMBL11770403 | 0.85 | LTB4R (0.52) | LTB4RTTRRARBMEN1ALDH1A1 | |
| SCHEMBL11767118 | 0.85 | LTB4R (0.57) | LTB4RTTRRARBMEN1ALDH1A1 | |
| SCHEMBL11769752 | 0.84 | LTB4R (0.53) | LTB4RTTRRARBMEN1ALDH1A1 | |
| SCHEMBL11774822 | 0.84 | TTR (0.55) | LTB4RTTRMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3989721-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-11-02 | — | — | US | disclosed |
| US-3989720-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-11-02 | — | — | US | disclosed |
| US-3988352-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-10-26 | — | — | US | disclosed |
| US-3979414-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-09-07 | — | — | US | disclosed |
| US-3965115-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-06-22 | — | — | US | disclosed |
| US-3963753-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-06-15 | — | — | US | disclosed |
| US-3963752-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-06-15 | — | — | US | disclosed |