SCHEMBL1176730

SCHEMBL1176730

NC(CN1CCCCC1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 1/20 0.55
ANPEP P15144 1/20 0.52
ERAP2 Q6P179 1/20 0.52
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.42
MAPT P10636 3/20 0.42
ALDH1A1 P00352 2/20 0.42
HPGD P15428 1/20 0.42
CYP1A2 P05177 2/20 0.41
GRIK1 P39086 2/20 0.41
GSR P00390 2/20 0.41
GRM8 O00222 1/20 0.41
GRM6 O15303 1/20 0.41
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
GRM5 P41594 1/20 0.41
GRIA1 P42261 1/20 0.41
GRIA2 P42262 1/20 0.41
GRIA3 P42263 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2065181 1.00 DPP7 (0.55) DPP7ANPEPERAP2KMT2AMEN1
SCHEMBL384886 1.00 DPP7 (0.55) DPP7ANPEPERAP2KMT2AMEN1
Hydrochloric Acid SCHEMBL31323997 0.98 DPP7 (0.53) DPP7ANPEPERAP2KMT2AMEN1
SCHEMBL25661087 0.98 DPP7 (0.52) DPP7ANPEPERAP2KMT2AMEN1
SCHEMBL5322593 0.98 DPP7 (0.52) DPP7ANPEPERAP2KMT2AMEN1
SCHEMBL4637391 0.83 ANPEP (0.52) DPP7ANPEPERAP2KMT2AMEN1
SCHEMBL15049655 0.81 ALDH1A1 (0.61) DPP7ANPEPKMT2AMEN1MAPT
SCHEMBL1527303 0.81 DPP7 (0.53) DPP7ANPEPERAP2KMT2AL3MBTL1
SCHEMBL1527306 0.81 DPP7 (0.53) DPP7ANPEPERAP2KMT2AL3MBTL1
SCHEMBL5533637 0.81 ALDH1A1 (0.61) DPP7ANPEPKMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12134610-B2 Somatostatin subtype-2 receptor (SST2R) targeted therapeutics and uses thereof Crinetics Pharmaceuticals, Inc. (US) 2024-11-05 US claimed
CN-117957022-A Antisense compounds and methods for targeting CUG repeats 安卓达治疗股份有限公司 2024-04-30 CN claimed
CN-117915957-A Compositions and methods for modulating mRNA splicing 恩特拉达治疗学股份有限公司 2024-04-19 CN claimed
CN-117561271-A Cyclic cell penetrating peptides 恩特拉达治疗公司 2024-02-13 CN claimed
EP-1879859-A2 DIARYLSULFONE SULFONAMIDES AND USE THEROF Wyeth a Corporation of the State of Delaware (US) 2008-01-23 EP claimed
WO-2006124875-A2 DIARYLSULFONE SULFONAMIDES AND USE THEROF WYETH (US) 2006-11-23 WO claimed
US-20250289851-A1 CYCLIC PEPTIDES FOR DELIVERING THERAPEUTICS ENTRADA THERAPEUTICS, INC. 2025-09-18 US disclosed
CN-118284434-A Compositions and methods for skipping exon 45 in duchenne muscular dystrophy 恩特拉达治疗学股份有限公司 2024-07-02 CN disclosed
CN-118215504-A Compounds and methods for skipping exon 44 in duchenne muscular dystrophy 恩特拉达治疗学股份有限公司 2024-06-18 CN disclosed
CN-117957022-A Antisense compounds and methods for targeting CUG repeats 安卓达治疗股份有限公司 2024-04-30 CN disclosed
CN-117915957-A Compositions and methods for modulating mRNA splicing 恩特拉达治疗学股份有限公司 2024-04-19 CN disclosed
CN-117897176-A Compositions and methods for modulating tissue distribution of intracellular therapeutic agents 恩特拉达治疗学股份有限公司 2024-04-16 CN disclosed
CN-117561271-A Cyclic cell penetrating peptides 恩特拉达治疗公司 2024-02-13 CN disclosed
WO-2005112922-A2 BENZAMIDE COMPOUNDS SAMARITAN PHARMACEUTICALS (US) 2005-12-01 WO disclosed
WO-2005000205-A2 METHODS AND COMPOSITIONS FOR MODULATING SERUM CORTISOL LEVELS SAMARITAN PHARMACEUTICALS, INC. (US) 2005-01-06 WO disclosed
WO-2004108076-A2 ANTI-HIV BENZAMIDE COMPOUNDS SAMARITAN PHARMACEUTICALS, INC. (US) 2004-12-16 WO disclosed
US-5401722-A Peptide analogues MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-03-28 US disclosed
US-5378691-A Amino acid derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-01-03 US disclosed
US-5215967-A AMINOACID DERIVATIVES INHIBITING RENIN MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1993-06-01 US disclosed
CN-1037155-A Amino acid derivative MERCK PATENT GMBH (DE) 1989-11-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12134610-B2 Somatostatin subtype-2 receptor (SST2R) targeted therapeutics and uses thereof SSTR2, SSTR1, SSTR4 DPP7 315/4885ANPEP 565/4885ERAP2 662/4885
US-20250289851-A1 CYCLIC PEPTIDES FOR DELIVERING THERAPEUTICS IAPP, LNPEP, CFTR DPP7 292/4885ANPEP 98/4885ERAP2 34/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.