Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 7/20 | 0.54 |
| ▸ | MAOB | P27338 | 12/20 | 0.48 |
| ▸ | MAOA | P21397 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | SDHA | P31040 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6961990 | 0.89 | CALML3 (0.55) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL6967427 | 0.89 | CALML3 (0.51) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL6961277 | 0.87 | CALML3 (0.54) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL6974073 | 0.86 | MAOA (0.69) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL1176771 | 0.86 | MAOA (0.69) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL1176669 | 0.85 | MAOB (0.50) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL8173015 | 0.83 | MAOB (0.46) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL14597079 | 0.82 | CALML3 (0.55) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL29196827 | 0.82 | CALML3 (0.55) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL29196830 | 0.82 | CALML3 (0.55) | CALML3MAOBMAOALMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7892574-B2 | In situ applying oxazolidinone to ear, skins | PHARMACIA & UPJOHN COMPANY, LLC (US) | 2011-02-22 | — | — | US | disclosed |
| EP-1096934-B1 | OXAZOLIDINONES TO TREAT EYE INFECTIONS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-21 | — | — | EP | disclosed |
| EP-1304107-B1 | Use of oxazolidinines derivatives for treating psoriasis | PHARMACIA & UPJOHN CO LLC (US) | 2005-07-06 | — | — | EP | disclosed |
| US-6740652-B2 | Oxazolidinones to treat eye infections | PHARMACIA & UPJOHN COMPANY | 2004-05-25 | — | — | US | disclosed |
| US-20040072841-A1 | Topical administration of oxazolidinones for transdermal delivery | FORD CHARLES W (US) | 2004-04-15 | — | — | US | disclosed |
| US-6613349-B2 | Administration of oxazolidinones for transdermal delivery | PHARMACIA & UPJOHN COMPANY | 2003-09-02 | — | — | US | disclosed |
| EP-1304107-A2 | Use of oxazolidinines derivatives for treating psoriasis | PHARMACIA & UPJOHN COMPANY (US) | 2003-04-23 | — | — | EP | disclosed |
| EP-0882041-B1 | PIPERAZINONEPHENYLOXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2003-03-26 | — | — | EP | disclosed |
| EP-1032386-B1 | USE OF OXAZOLIDINONE DERIVATIVES FOR TREATING ARTHRITIS | UPJOHN CO (US) | 2003-02-26 | — | — | EP | disclosed |
| EP-1083900-B1 | USE OF OF OXAZOLIDINONES FOR THE PREPARATION OF A MEDICAMENT FOR TRANSDERMAL DELIVERY | UPJOHN CO (US) | 2002-07-17 | — | — | EP | disclosed |
| US-20020065280-A1 | Oxazolidinones to treat eye infections | COCHRAN ROBERT J (US) | 2002-05-30 | — | — | US | disclosed |
| US-20020009483-A1 | TOPICAL ADMINISTRATION OF OXAZOLIDINONES FOR TRANSDERMAL DELIVERY | PHARMACIA & UPJOHN COMPANY | 2002-01-24 | — | — | US | disclosed |
| US-6337329-B1 | Oxazolidinones to treat eye infections | PHARMACIA & UPJOHN COMPANY | 2002-01-08 | — | — | US | disclosed |
| US-6069145-A | AGAINST ANTIBIOTIC RESISTANT BACTERIA | ZENECA LIMITED (GB) | 2000-05-30 | — | — | US | disclosed |
| US-6040306-A | Method of treating psoriasis, arthritis and reducing the toxicity of cancer chemotherapy | PHARMACIA & UPJOHN COMPANY | 2000-03-21 | — | — | US | disclosed |
| EP-0882041-A1 | PIPERAZINONEPHENYLOXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | AstraZeneca AB (SE) | 1998-12-09 | — | — | EP | disclosed |
| WO-1997027188-A1 | PIPERAZINONEPHENYLOXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ZENECA LIMITED (GB) | 1997-07-31 | — | — | WO | disclosed |