Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 7/20 | 0.55 |
| ▸ | MAOB | P27338 | 12/20 | 0.53 |
| ▸ | MAOA | P21397 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | SDHA | P31040 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1176740 | 0.89 | CALML3 (0.54) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL6961277 | 0.88 | CALML3 (0.54) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL6967427 | 0.88 | CALML3 (0.51) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL6975181 | 0.87 | MAOA (0.71) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL6976519 | 0.87 | MAOA (0.71) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL8594959 | 0.85 | MAOB (0.51) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL6962239 | 0.85 | MAOB (0.51) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL14597080 | 0.82 | CALML3 (0.55) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL14597079 | 0.82 | CALML3 (0.55) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL5383852 | 0.82 | CALML3 (0.55) | CALML3MAOBMAOALMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882041-B1 | PIPERAZINONEPHENYLOXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2003-03-26 | — | — | EP | disclosed |
| US-6069145-A | AGAINST ANTIBIOTIC RESISTANT BACTERIA | ZENECA LIMITED (GB) | 2000-05-30 | — | — | US | disclosed |
| EP-0882041-A1 | PIPERAZINONEPHENYLOXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | AstraZeneca AB (SE) | 1998-12-09 | — | — | EP | disclosed |
| WO-1997027188-A1 | PIPERAZINONEPHENYLOXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ZENECA LIMITED (GB) | 1997-07-31 | — | — | WO | disclosed |