SCHEMBL11768367

SCHEMBL11768367

O=C(O)Cl.Sc1cccc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.50
NR4A2 P43354 1/20 0.50
NR4A3 Q92570 1/20 0.50
MAPT P10636 3/20 0.48
HDAC8 Q9BY41 2/20 0.48
TDP1 Q9NUW8 2/20 0.46
CDC25B P30305 1/20 0.44
WDR5 P61964 1/20 0.42
CTNNB1 P35222 1/20 0.42
CYP1A2 P05177 4/20 0.42
KDM4E B2RXH2 4/20 0.42
ALDH1A1 P00352 3/20 0.42
CYP2C19 P33261 2/20 0.42
HPGD P15428 2/20 0.42
NPC1 O15118 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
RAB9A P51151 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2647 0.84 ALDH1A1 (0.53) NR4A1NR4A2NR4A3TDP1CDC25B
SCHEMBL10410487 0.82 ALDH1A1 (0.50) NR4A1NR4A2NR4A3TDP1CDC25B
Potassium SCHEMBL10410489 0.82 ALDH1A1 (0.50) NR4A1NR4A2NR4A3TDP1CDC25B
SCHEMBL7739907 0.82 ALDH1A1 (0.50) NR4A1NR4A2NR4A3TDP1CDC25B
SCHEMBL7330141 0.82 ALDH1A1 (0.50) NR4A1NR4A2NR4A3TDP1CDC25B
Phenol SCHEMBL28223858 0.81 CYP1A2 (0.48) NR4A1NR4A2NR4A3MAPTTDP1
Benzenethiol SCHEMBL28087569 0.80 ALDH1A1 (0.43) NR4A1NR4A2NR4A3TDP1CDC25B
SCHEMBL31604194 0.80 CYP1A2 (0.46) NR4A1NR4A2NR4A3HDAC8TDP1
SCHEMBL27851728 0.78 ALDH1A1 (0.46) NR4A1NR4A2NR4A3TDP1CDC25B
Pyridine SCHEMBL28146904 0.75 PSMD14 (0.41) NR4A1NR4A2NR4A3MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4059609-A HERBICIDE, NEMATOCIDE, FUNGICIDE PPG INDUSTRIES, INC. (US) 1977-11-22 US disclosed