SCHEMBL11768554

SCHEMBL11768554

CCn1c(=O)[nH]c(=O)n(-c2ccc(Sc3ccc(Cl)cc3Cl)c(Cl)c2)c1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
TSHR P16473 1/20 0.38
NFKB1 P19838 1/20 0.38
BLM P54132 1/20 0.38
PMP22 Q01453 1/20 0.38
ITGB2 P05107 2/20 0.38
ICAM1 P05362 2/20 0.38
ITGAL P20701 2/20 0.38
BRD9 Q9H8M2 2/20 0.37
PGR P06401 1/20 0.37
NTRK1 P04629 2/20 0.36
NTRK3 Q16288 2/20 0.36
NTRK2 Q16620 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11772473 0.84 NOTUM (0.41) NOTUMSMN1; SMN2MEN1KMT2ALMNA
SCHEMBL11768070 0.81 NPSR1 (0.37) NOTUMMEN1KMT2ALMNARHEB
SCHEMBL11680403 0.81 SMN1; SMN2 (0.50) SMN1; SMN2MEN1KMT2ALMNACYP1A2
SCHEMBL11770055 0.80 PDE7A (0.46) SMN1; SMN2MEN1KMT2ALMNACYP1A2
SCHEMBL11772410 0.78 PKM (0.45) SMN1; SMN2MEN1KMT2ALMNACYP1A2
SCHEMBL11768727 0.77 AR (0.40) SMN1; SMN2MEN1KMT2ALMNACYP1A2
SCHEMBL11769331 0.77 DDR1 (0.42) SMN1; SMN2MEN1KMT2ALMNACYP1A2
SCHEMBL11770350 0.77 DDR1 (0.39) SMN1; SMN2MEN1KMT2ALMNACYP1A2
SCHEMBL11769259 0.76 MEN1 (0.40) SMN1; SMN2MEN1KMT2ALMNACYP1A2
SCHEMBL11818096 0.76 PDE7A (0.43) SMN1; SMN2MEN1KMT2ALMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3970752-A Coccidiocidal compositions utilizing 1-phenyl-substituted 1,3,5-triazine BAYER AKTIENGESELLSCHAFT (DT) 1976-07-20 US disclosed
US-3948893-A COCCIDIOSIS BAYER AKTIENGESELLSCHAFT (DT) 1976-04-06 US disclosed