Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.43 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.43 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11772410 | 0.93 | PKM (0.45) | SMN1; SMN2NPC1NPSR1NTRK1NTRK3 | |
| SCHEMBL11770893 | 0.90 | SMN1; SMN2 (0.43) | SMN1; SMN2NPC1NPSR1NTRK1NTRK3 | |
| SCHEMBL11770297 | 0.89 | SMN1; SMN2 (0.42) | SMN1; SMN2NPC1NPSR1NTRK1NTRK3 | |
| SCHEMBL11684045 | 0.83 | PGR (0.54) | NTRK1NTRK3NTRK2GSK3AGSK3B | |
| SCHEMBL11768554 | 0.81 | NOTUM (0.39) | SMN1; SMN2NTRK1NTRK3NTRK2KMT2A | |
| SCHEMBL11766192 | 0.80 | PKM (0.59) | SMN1; SMN2NPC1NPSR1NTRK1NTRK3 | |
| SCHEMBL11767854 | 0.79 | PKM (0.44) | SMN1; SMN2NTRK1NTRK3NTRK2POLB | |
| SCHEMBL11768173 | 0.79 | NPC1 (0.46) | SMN1; SMN2NPC1NPSR1NTRK1NTRK3 | |
| SCHEMBL11771509 | 0.78 | PKM (0.43) | SMN1; SMN2NPSR1KMT2AMEN1CYP1A2 | |
| SCHEMBL11770892 | 0.78 | CA9 (0.49) | SMN1; SMN2NPC1NPSR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4056527-A | HERBICIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-01 | — | — | US | disclosed |