SCHEMBL11768622

SCHEMBL11768622

O=C(O)n1c(C(F)(F)F)nc2cc(Cl)c(Cl)cc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
GAA P10253 2/20 0.35
MGAM O43451 1/20 0.35
AMY1A P0DUB6 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
PPARG P37231 1/20 0.35
GLP1R P43220 1/20 0.35
TTR P02766 1/20 0.34
RHEB Q15382 1/20 0.34
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GLA P06280 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4658983 0.90 CYP1A2 (0.34) CYP1A2CYP2D6CYP2C9CYP2C19PPARG
SCHEMBL29394219 0.80 ALDH1A1 (0.45) CYP1A2CYP2D6CYP2C9CYP2C19GAA
SCHEMBL118829 0.80 ALDH1A1 (0.45) CYP1A2CYP2D6CYP2C9CYP2C19GAA
SCHEMBL6738861 0.78 GAA (0.43) GAAMGAMAMY1ASIMGAM2
SCHEMBL11510726 0.78 ALDH1A1 (0.38) CYP1A2CYP2D6CYP2C9CYP2C19GAA
SCHEMBL4660132 0.72 ALDH1A1 (0.40) CYP1A2CYP2D6CYP2C9CYP2C19GAA
SCHEMBL11685572 0.71 PPARG (0.34) GAAPPARGGLP1RKDM4EMEN1
SCHEMBL11482358 0.69 CYP1A2 (0.33) CYP1A2CYP2C9HPGD
SCHEMBL8623725 0.67 KDM4E (0.50) CYP1A2CYP2D6CYP2C9CYP2C19GAA
SCHEMBL4660245 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4007258-A Sustained release pesticidal composition UNION CORPORATION (US) 1977-02-08 US disclosed