Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | SNCA | P37840 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | P4HB | P07237 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11769170 | 1.00 | MAOB (0.53) | MAOBSNCAPOLBCYP2A6KMT2A | |
| SCHEMBL11767686 | 0.90 | THRB (0.52) | MAOBSNCAKMT2AMAPTLMNA | |
| SCHEMBL11767692 | 0.90 | THRB (0.52) | MAOBSNCAKMT2AMAPTLMNA | |
| SCHEMBL12154213 | 0.89 | POLB (0.62) | MAOBPOLBKMT2AMAPTLMNA | |
| SCHEMBL11765937 | 0.87 | SNCA (0.52) | SNCAKMT2AMAPTLMNAHDAC2 | |
| SCHEMBL11765941 | 0.87 | SNCA (0.52) | SNCAKMT2AMAPTLMNAHDAC2 | |
| SCHEMBL11764696 | 0.86 | THRB (0.55) | SNCAKMT2AALDH1A1RAB9AMGLL | |
| SCHEMBL11764699 | 0.86 | THRB (0.55) | SNCAKMT2AALDH1A1RAB9AMGLL | |
| SCHEMBL11662877 | 0.85 | ABCG2 (0.54) | SNCAKMT2AMAPTHDAC2ALDH1A1 | |
| SCHEMBL11761761 | 0.85 | TSHR (0.54) | SNCAALDH1A1RAB9AMGLLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061587-A | Liquid crystalline cinnamic acid esters | HOFFMANN-LA ROCHE INC. (US) | 1977-12-06 | — | — | US | disclosed |