Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sorbitol SCHEMBL2199729 | 0.88 | LMNA (0.55) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Mannitol SCHEMBL27482485 | 0.88 | LMNA (0.55) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Glycerin SCHEMBL2357917 | 0.84 | ALDH1A1 (0.38) | LMNAUSP2 | |
| Xylitol SCHEMBL9438052 | 0.83 | LMNA (0.48) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Mannitol SCHEMBL3909131 | 0.83 | LMNA (0.61) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Mannitol SCHEMBL11015104 | 0.83 | LMNA (0.61) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Sorbitol SCHEMBL619756 | 0.83 | LMNA (0.61) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Mannitol SCHEMBL27466965 | 0.82 | LMNA (0.48) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Sorbitol SCHEMBL15663030 | 0.82 | LMNA (0.48) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Sorbitol SCHEMBL10719880 | 0.82 | LMNA (0.48) | LMNAL3MBTL1TDP1KDM4EPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4032485-A | POLYURETHANE FOAMS BASED ON MIXED ITACONIC ACID POLYESTERS | MIYOSHI YUSHI KABUSHIKI KAISHA (JA) | 1977-06-28 | — | — | US | claimed |