Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | GRM8 | O00222 | 1/20 | 0.60 |
| ▸ | GRM6 | O15303 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1955154 | 0.98 | HSD17B10 (0.62) | HSD17B10TDP1MEN1CYP2C9KMT2A | |
| SCHEMBL11770761 | 0.84 | HSD17B10 (0.53) | HSD17B10TDP1MEN1CYP2C9KMT2A | |
| SCHEMBL19886217 | 0.84 | HSD17B10 (0.49) | HSD17B10TDP1MEN1CYP2C9KMT2A | |
| SCHEMBL9269600 | 0.82 | HSD17B10 (0.47) | HSD17B10TDP1MEN1CYP2C9KMT2A | |
| SCHEMBL8908076 | 0.81 | HSD17B10 (0.46) | HSD17B10TDP1MEN1CYP2C9KMT2A | |
| SCHEMBL9269604 | 0.81 | HSD17B10 (0.46) | HSD17B10TDP1MEN1CYP2C9KMT2A | |
| SCHEMBL9853831 | 0.81 | HSD17B10 (0.58) | HSD17B10TDP1MEN1CYP2C9KMT2A | |
| SCHEMBL25017789 | 0.80 | KDM4E (0.59) | HSD17B10TDP1MEN1CYP2C9KMT2A | |
| SCHEMBL1356399 | 0.78 | HSD17B10 (0.60) | HSD17B10TDP1MEN1CYP2C9KMT2A | |
| SCHEMBL29401129 | 0.78 | HSD17B10 (0.60) | HSD17B10TDP1MEN1CYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933745-A | Imide copolymers possessing hydroxyl groups | RHONE-POULENC S.A. (FR) | 1976-01-20 | — | — | US | disclosed |