Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | GRM8 | O00222 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9269600 | 0.97 | HSD17B10 (0.47) | HSD17B10TDP1MEN1KMT2ACYP2C9 | |
| SCHEMBL8908076 | 0.93 | HSD17B10 (0.46) | HSD17B10TDP1MEN1KMT2ACYP2C9 | |
| SCHEMBL10632616 | 0.91 | CA12 (0.47) | HSD17B10KMT2ACA12CA1CA2 | |
| SCHEMBL1955154 | 0.83 | HSD17B10 (0.62) | HSD17B10TDP1MEN1KMT2ACYP2C9 | |
| SCHEMBL11770754 | 0.81 | HSD17B10 (0.60) | HSD17B10TDP1MEN1KMT2ACYP2C9 | |
| SCHEMBL9269593 | 0.79 | CA12 (0.51) | HSD17B10TDP1MEN1KMT2ACYP2C9 | |
| SCHEMBL338081 | 0.78 | CFD (0.50) | HSD17B10KMT2ACYP2C9CYP2C19CYP2D6 | |
| SCHEMBL8992908 | 0.78 | PPARA (0.45) | HSD17B10KMT2ASLC6A2SLC6A4CA12 | |
| SCHEMBL19976131 | 0.77 | CA12 (0.44) | HSD17B10KMT2ACA12CA1CA2 | |
| SCHEMBL21090566 | 0.77 | CA12 (0.47) | HSD17B10MEN1KMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4736015-A | FROM DI-(ORTETRA) ESTER OF BENZHYDROL 3,3*,4,4*-TETRACARBOXYLIC ACID AND AROMATIC DIAMINE | INSTITUT FRANCAIS DU PETROLE (FR) | 1988-04-05 | — | — | US | claimed |
| US-5378799-A | Heat-stable polyimides and polyamide-imides with modified benzhydrol structural elements and their preparation | CHEMIE LINZ GMBH (AT) | 1995-01-03 | — | — | US | disclosed |
| US-4851506-A | Photostructurable polyimide mixtures | CIBA-GEIGY CORPORATION (US) | 1989-07-25 | — | — | US | disclosed |
| US-4736015-A | FROM DI-(ORTETRA) ESTER OF BENZHYDROL 3,3*,4,4*-TETRACARBOXYLIC ACID AND AROMATIC DIAMINE | INSTITUT FRANCAIS DU PETROLE (FR) | 1988-04-05 | — | — | US | disclosed |