Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 2/20 | 0.52 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | GRN | P28799 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24896204 | 0.83 | TPMT (0.55) | TPMTHCAR1APEX1HCAR2TTR | |
| SCHEMBL29199640 | 0.80 | TPMT (0.52) | TPMTHCAR1APEX1HCAR2TTR | |
| SCHEMBL30866611 | 0.80 | TPMT (0.52) | TPMTHCAR1APEX1HCAR2TTR | |
| SCHEMBL11770949 | 0.77 | TPMT (0.61) | TPMTHCAR1HCAR2TTRRXRA | |
| SCHEMBL22926034 | 0.75 | TPMT (0.50) | TPMTHCAR1APEX1HCAR2TTR | |
| SCHEMBL670993 | 0.75 | APEX1 (0.75) | APEX1PKMALOX15HSD17B10HPGD | |
| SCHEMBL21484252 | 0.74 | TPMT (0.64) | TPMTHCAR1HCAR2TTRRXRA | |
| SCHEMBL14309133 | 0.73 | PKM (0.54) | APEX1PKMTSHRHPGDALDH1A1 | |
| SCHEMBL23375759 | 0.72 | TPMT (0.55) | TPMTHCAR1HCAR2TTRRXRA | |
| SCHEMBL23375602 | 0.72 | TPMT (0.55) | TPMTHCAR1HCAR2TTRRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953595-A | Substituted benzoic acid hypolipemic agents | PFIZER INC. (US) | 1976-04-27 | — | — | US | disclosed |