Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 2/20 | 0.52 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30866611 | 1.00 | TPMT (0.52) | TPMTHCAR1PLA2G2ATHRBHCAR2 | |
| SCHEMBL11941049 | 0.88 | PLA2G2A (0.43) | TPMTPLA2G2AAPEX1MAPTCYP1A2 | |
| SCHEMBL24896204 | 0.86 | TPMT (0.55) | TPMTHCAR1HCAR2TTRCTRC | |
| SCHEMBL15054145 | 0.80 | MAPT (0.53) | TPMTPLA2G2ATHRBAPEX1MAPT | |
| SCHEMBL11771729 | 0.80 | TPMT (0.52) | TPMTHCAR1HCAR2TTRCTRC | |
| SCHEMBL11941047 | 0.77 | PLA2G2A (0.49) | PLA2G2ATHRBTSHR | |
| SCHEMBL11770949 | 0.77 | TPMT (0.61) | TPMTHCAR1HCAR2TTRCTRC | |
| SCHEMBL11941048 | 0.76 | PLA2G2A (0.51) | PLA2G2ATHRBTSHR | |
| SCHEMBL22926034 | 0.75 | TPMT (0.50) | TPMTHCAR1HCAR2TTRCTRC | |
| SCHEMBL15054482 | 0.75 | MAPT (0.62) | MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112424201-B | Protein kinase inhibitors that promote liver regeneration or reduce or prevent hepatocyte death | 海帕瑞吉尼克斯股份有限公司 | 2024-04-02 | — | — | CN | disclosed |