Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.48 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4855348 | 0.78 | KCNN4 (0.43) | KCNN4MAPK1KDM4ELMNATAAR1 | |
| SCHEMBL10007041 | 0.78 | KCNN4 (0.43) | KCNN4DPP4TSHRF2ALDH1A1 | |
| SCHEMBL10006934 | 0.78 | KCNN4 (0.43) | KCNN4DPP4TSHRF2ALDH1A1 | |
| SCHEMBL17077295 | 0.76 | ADRA2A (0.43) | KCNN4ALDH1A1MAPK1KDM4ELMNA | |
| SCHEMBL28351446 | 0.76 | CYP1A2 (0.42) | KCNN4ALDH1A1MAPK1KDM4ELMNA | |
| SCHEMBL28351447 | 0.76 | CYP1A2 (0.42) | KCNN4ALDH1A1MAPK1KDM4ELMNA | |
| SCHEMBL938787 | 0.74 | TAAR1 (0.43) | KCNN4MAPK1KDM4ELMNATAAR1 | |
| Ammonia Solution, Strong SCHEMBL1484878 | 0.74 | CYP1A2 (0.41) | KCNN4ALDH1A1MAPK1KDM4ELMNA | |
| SCHEMBL7396324 | 0.74 | KCNN4 (0.40) | KCNN4DPP4TSHRF2ALDH1A1 | |
| SCHEMBL29351710 | 0.72 | KIF11 (0.48) | KIF11CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042620-A | Continuous process for the production of maeamic acids | RHONE-POULENC, S.A. (FR) | 1977-08-16 | — | — | US | disclosed |
| US-3960887-A | Continuous process for the preparation of maleimides | RHONE-POULENC S.A. (FR) | 1976-06-01 | — | — | US | disclosed |
| US-3947493-A | Process for the production of maleamic acids | RHONE-POULENC, S.A. (FR) | 1976-03-30 | — | — | US | disclosed |