SCHEMBL11772386

CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSCc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)NC(=O)OCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	NPY1R	P25929	3/20	0.48

▸	NMUR2	Q9GZQ4	7/20	0.45

▸	NMUR1	Q9HB89	7/20	0.45

▸	NPY2R	P49146	1/20	0.45

▸	NPY4R	P50391	1/20	0.45

▸	NPY5R	Q15761	1/20	0.45

▸	OPRD1	P41143	2/20	0.44

▸	REN	P00797	1/20	0.44

▸	F2	P00734	3/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL11774049	0.97	NPY1R (0.48)	NPY1RNMUR2NMUR1NPY2RNPY4R
SCHEMBL11773038	0.92	REN (0.47)	NMUR2NMUR1OPRD1REN
SCHEMBL11773146	0.91	NMUR2 (0.49)	NMUR2NMUR1OPRD1REN
SCHEMBL11772396	0.89	NPY1R (0.47)	NPY1RNMUR2NMUR1NPY2RNPY4R
SCHEMBL11772364	0.89	NPY1R (0.47)	NPY1RNMUR2NMUR1NPY2RNPY4R
SCHEMBL11773025	0.88	REN (0.51)	NMUR2NMUR1REN
SCHEMBL11773078	0.88	REN (0.51)	NMUR2NMUR1REN
SCHEMBL11771442	0.87	NPY1R (0.51)	NPY1RNMUR2NMUR1NPY2RNPY4R
SCHEMBL11771428	0.87	NPY1R (0.51)	NPY1RNMUR2NMUR1NPY2RNPY4R
SCHEMBL7309484	0.87	NPY1R (0.51)	NPY1RNMUR2NMUR1NPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-3960828-A	Catalytic hydrogenolysis of protected sulfur containing peptides	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US)	1976-06-01	—	—	US	disclosed