Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11769642 | 0.89 | CHRM2 (0.35) | HTR2ACHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11772330 | 0.87 | HTR1A (0.34) | HTR2ACHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11771917 | 0.86 | CHRM2 (0.37) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL11767082 | 0.86 | CHRM2 (0.37) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL11767677 | 0.83 | SLC6A2 (0.35) | HTR2ACHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11767690 | 0.83 | CHRM2 (0.35) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL11774087 | 0.83 | ADRA2A (0.33) | HTR2ACHRM2HTR1AADRA2ACHRM1 | |
| Hydrochloric Acid SCHEMBL11771572 | 0.82 | SLC6A2 (0.36) | HTR2ACHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11767726 | 0.81 | UTS2R (0.42) | HTR2ACHRM2HTR1AADRA2ACHRM1 | |
| Pirandamine SCHEMBL585038 | 0.81 | UTS2R (0.43) | HTR2ACHRM2HTR1AADRA2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3995052-A | Indenopyran- and indenothiopyranalkylamines III in the treatment of depression | AYERST MCKENNA AND HARRISON LTD. (CA) | 1976-11-30 | — | — | US | disclosed |