Stearic Acid

SCHEMBL11772995

CCCCCCCCCCCCCCCCCC(=O)[O-].CCCCCCCCCCCCCCCCCC(=O)[O-].CCCCc1ccc(C(=O)[O-])c(C(=O)[O-])c1CCCC.CCCCc1ccc(C(=O)[O-])c(C(=O)[O-])c1CCCC.[Zn+2].[Zn+2].[Zn+2]

nearest known ligand 0.45

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Known targets — ChEMBL curated mechanism

rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	FABP3	P05413	7/20	0.40

▸	CA1	P00915	1/20	0.37

▸	CNR2	P34972	1/20	0.36

▸	PPARG	P37231	1/20	0.36

▸	TYR	P14679	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Stearic Acid SCHEMBL11773002	0.91	GPR84 (0.42)	FABP3PPARG
SCHEMBL3630791	0.88	CNR2 (0.39)	CNR2PPARGTYR
SCHEMBL8880075	0.76	BID (0.39)	CNR2PPARGTYR
SCHEMBL21224597	0.76	TYR (0.39)	CNR2TYR
SCHEMBL8025056	0.74	HDAC3 (0.37)	CNR2
Stearic Acid SCHEMBL11772992	0.73	PPARG (0.45)	FABP3PPARG
Stearic Acid SCHEMBL9769935	0.73	BID (0.44)	FABP3PPARG
SCHEMBL5271574	0.72	PPARA (0.52)	PPARG
SCHEMBL5531460	0.72	PPARA (0.52)	PPARG
SCHEMBL5515490	0.72	PPARA (0.52)	PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-3991750-A	DROMOSTANOLONE PROPIONATE IMPLANT PELLET USEFUL FOR PRODUCING WEIGHT GAINS IN ANIMALS AND SUPPRESSING ESTRUS IN FEMALE ANIMALS	SYNTEX CORPORATION (US)	1976-11-16	—	—	US	disclosed