Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.48 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112414 | 0.79 | LMNA (0.56) | NPC1RAB9AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3661541 | 0.77 | PLAU (0.48) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL15771474 | 0.77 | MEN1 (0.52) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL12500219 | 0.77 | KDM4E (0.71) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL15229237 | 0.76 | NPC1 (0.59) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL28535180 | 0.75 | MEN1 (0.51) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL13009957 | 0.75 | KDM4E (0.52) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL11165331 | 0.75 | CRHBP (0.65) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL758293 | 0.75 | TSHR (0.47) | RAB9AMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL1095091 | 0.73 | MEN1 (0.61) | NPC1RAB9AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3976620-A | Phosphorus containing amides flame retardants | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |