SCHEMBL1177477

SCHEMBL1177477

COC(=O)CCC(=O)CN1C(=O)c2ccccc2C1=O

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
MAPT P10636 2/20 0.55
POLB P06746 2/20 0.53
CA12 O43570 1/20 0.53
CA9 Q16790 1/20 0.53
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
NPC1 O15118 1/20 0.51
NPSR1 Q6W5P4 2/20 0.50
KDM4E B2RXH2 1/20 0.50
RAB9A P51151 1/20 0.50
TDP1 Q9NUW8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30522630 1.00 ALDH1A1 (0.55) ALDH1A1MAPTPOLBCA12CA9
SCHEMBL588758 0.87 ALDH1A1 (0.57) ALDH1A1MAPTPOLBCA12CA9
SCHEMBL524126 0.85 ALDH1A1 (0.67) ALDH1A1MAPTPOLBCA12CA9
SCHEMBL22957156 0.83 CA12 (0.51) ALDH1A1MAPTPOLBCA12CA9
SCHEMBL12235840 0.82 HPGD (0.62) ALDH1A1MAPTPOLBKMT2AMEN1
SCHEMBL10671092 0.82 ALDH1A1 (0.59) ALDH1A1MAPTCA12CA9KMT2A
SCHEMBL10666782 0.82 CA12 (0.58) ALDH1A1MAPTCA12CA9KMT2A
SCHEMBL29602255 0.80 ALDH1A1 (0.59) ALDH1A1MAPTCA12CA9KMT2A
SCHEMBL1413232 0.80 CA12 (0.70) ALDH1A1MAPTPOLBCA12CA9
SCHEMBL28908599 0.79 KMT2A (0.70) ALDH1A1MAPTKMT2AMEN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116162038-A Environment-friendly production process of 5-aminolevulinic acid hydrochloride 河南省精细化工研究院有限公司 2023-05-26 CN claimed
CN-113416142-B Preparation method of 5-ALA intermediate 5-bromolevulinate 邯郸市赵都精细化工有限公司 2022-10-18 CN claimed
CN-113416142-A Preparation method of 5-ALA intermediate 5-bromolevulinate 邯郸市赵都精细化工有限公司 2021-09-21 CN claimed
CN-116162038-A Environment-friendly production process of 5-aminolevulinic acid hydrochloride 河南省精细化工研究院有限公司 2023-05-26 CN disclosed
CN-116162038-A Environment-friendly production process of 5-aminolevulinic acid hydrochloride 河南省精细化工研究院有限公司 2023-05-26 CN disclosed
CN-113416142-B Preparation method of 5-ALA intermediate 5-bromolevulinate 邯郸市赵都精细化工有限公司 2022-10-18 CN disclosed
CN-113416142-A Preparation method of 5-ALA intermediate 5-bromolevulinate 邯郸市赵都精细化工有限公司 2021-09-21 CN disclosed
US-8692014-B2 Acid addition salts of 5-aminolevulinic acid or its derivatives PHOTOCURE ASA (NO) 2014-04-08 US disclosed
CN-1938264-B Acid addition salts of 5-aminolevulinic acid or derivatives thereof PHOTOCURE ASA 2012-05-23 CN disclosed
US-20110125012-A1 ACID ADDITION SALTS OF 5-AMINOLEVULINIC ACID OR ITS DERIVATIVES BRAENDEN JON ERIK 2011-05-26 US disclosed
EP-2308830-A1 Acid addition salts of 5-aminolevulinic acid or its derivatives Photocure ASA (NO) 2011-04-13 EP disclosed
US-20080027233-A1 Process for the Preparation of Alkyl 5-(Dicarboximido) Levulinate and Alkyl 4-Oxopentenoate ESQUIRE AB (SE) 2008-01-31 US disclosed
US-7319164-B2 5-azido-laevulinic acid, method for the production thereof and its use ALDENKORTT SVEN 2008-01-15 US disclosed
EP-1833790-A1 PROCESS FOR THE PREPARATION OF ALKYL 5-(DICARBOXIMIDO)LEVULINATE AND ALKYL 4-OXO-PENTENOATE Biosynth AB (SE) 2007-09-19 EP disclosed
CN-1938264-A Acid addition salts of 5-aminolevulinic acid or derivatives thereof PHOTOCURE ASA (NO) 2007-03-28 CN disclosed
EP-1727786-A1 ACID ADDITION SALTS OF 5-AMINOLEVULINIC ACID OR ITS DERIVATIVES Photocure ASA (NO) 2006-12-06 EP disclosed
WO-2006048236-A1 PROCESS FOR THE PREPARATION OF ALKYL 5- (DICARBOXIMIDO) LEVULINATE AND ALKYL 4-OXO-PENTENOATE BIOSYNTH AB (SE) 2006-05-11 WO disclosed
US-20060086443-A1 5-azido-laevulinic acid, method for the production thereof and its use ALDENKORTT SVEN 2006-04-27 US disclosed
WO-2005092838-A1 ACID ADDITION SALTS OF 5-AMINOLEVULINIC ACID OR ITS DERIVATIVES PHOTOCURE ASA (NO) 2005-10-06 WO disclosed
US-20050070727-A1 Method for obtaining 5-halogenolaevulinic acid alkyl esters ALDENKORTT DR SVEN (DE) 2005-03-31 US disclosed