⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3517149 | 0.83 | — | — | |
| SCHEMBL781569 | 0.81 | TRPA1 (0.33) | — | |
| SCHEMBL19549311 | 0.79 | TSHR (0.34) | — | |
| SCHEMBL731665 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL15110455 | 0.73 | — | — | |
| SCHEMBL5785547 | 0.71 | — | — | |
| SCHEMBL9511513 | 0.71 | — | — | |
| SCHEMBL11877737 | 0.69 | — | — | |
| SCHEMBL11574622 | 0.68 | — | — | |
| SCHEMBL1820972 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8586369-B2 | Ion channel-forming peptides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-11-19 | — | — | US | disclosed |
| US-20110046020-A1 | NOVEL ION CHANNEL-FORMING PEPTIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-02-24 | — | — | US | disclosed |
| WO-2009009613-A2 | NOVEL ION CHANNEL-FORMING PEPTIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-01-15 | — | — | WO | disclosed |
| EP-0683676-A4 | DIRECTED BIODISTRIBUTION OF SMALL MOLECULES. | NEORX CORP (US) | 1998-09-30 | — | — | EP | disclosed |
| US-5607659-A | Directed biodistribution of radiolabelled biotin using carbohydrate polymers | NEORX CORPORATION (US) | 1997-03-04 | — | — | US | disclosed |
| EP-0683676-A1 | DIRECTED BIODISTRIBUTION OF SMALL MOLECULES | NEORX CORPORATION (US) | 1995-11-29 | — | — | EP | disclosed |
| WO-1994017829-A1 | DIRECTED BIODISTRIBUTION OF SMALL MOLECULES | NEORX CORPORATION (US) | 1994-08-18 | — | — | WO | disclosed |