Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CD38 | P28907 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11815461 | 0.84 | CYP19A1 (0.61) | CYP19A1IDO1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL11776292 | 0.84 | ALDH1A1 (0.56) | CYP19A1IDO1MAPTKMT2AMEN1 | |
| SCHEMBL11776129 | 0.84 | ALDH1A1 (0.53) | CYP19A1IDO1MAPTCD38CYP3A4 | |
| SCHEMBL11777233 | 0.84 | HCRTR1 (0.42) | IDO1HCRTR1CCR3CD38CYP3A4 | |
| SCHEMBL11863573 | 0.83 | MAPK14 (0.43) | MAPTCYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11802077 | 0.83 | CYP19A1 (0.56) | CYP19A1IDO1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL30764860 | 0.81 | CD38 (0.42) | IDO1HCRTR1CCR3CD38CYP3A4 | |
| SCHEMBL10912944 | 0.80 | CYP19A1 (0.64) | CYP19A1MAPTCYP3A4CYP1A2CYP2D6 | |
| SCHEMBL11778364 | 0.76 | IDO1 (0.56) | CYP19A1IDO1CD38KMT2AMEN1 | |
| SCHEMBL11776810 | 0.76 | IDO1 (0.55) | IDO1CD38CYP3A4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941802-A | 2-(Imidazol-1-yl)benzophenones | THE UPJOHN COMPANY (US) | 1976-03-02 | — | — | US | claimed |
| US-3992400-A | 1-(α-Phenyl-o-tolyl)imidazoles | THE UPJOHN COMPANY (US) | 1976-11-16 | — | — | US | disclosed |
| US-3941803-A | 2-(Imidazol-1-yl)benzophenones | THE UPJOHN COMPANY (US) | 1976-03-02 | — | — | US | disclosed |
| US-3941802-A | 2-(Imidazol-1-yl)benzophenones | THE UPJOHN COMPANY (US) | 1976-03-02 | — | — | US | disclosed |