Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CD38 | P28907 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11776292 | 0.90 | ALDH1A1 (0.56) | IDO1MEN1KMT2AMITFALDH1A1 | |
| SCHEMBL11861114 | 0.83 | ALDH1A1 (0.51) | MITFALDH1A1HSP90AA1HTTATM | |
| SCHEMBL11802077 | 0.83 | CYP19A1 (0.56) | IDO1MEN1KMT2AALDH1A1HSP90AA1 | |
| SCHEMBL11775805 | 0.83 | MEN1 (0.55) | IDO1MEN1KMT2AALDH1A1CYP19A1 | |
| SCHEMBL11776810 | 0.81 | IDO1 (0.55) | IDO1MEN1KMT2AMITFALDH1A1 | |
| SCHEMBL27730339 | 0.79 | ADH5 (0.57) | IDO1MEN1KMT2ACYP19A1NOTUM | |
| SCHEMBL11775302 | 0.76 | CYP19A1 (0.46) | IDO1MEN1KMT2AALDH1A1CYP19A1 | |
| SCHEMBL11815461 | 0.76 | CYP19A1 (0.61) | IDO1ALDH1A1HTTCYP19A1POLB | |
| SCHEMBL11776837 | 0.75 | RECQL (0.52) | IDO1MEN1KMT2AMITFALDH1A1 | |
| SCHEMBL7474779 | 0.74 | ALDH1A1 (0.45) | MEN1KMT2AMITFALDH1A1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3992400-A | 1-(α-Phenyl-o-tolyl)imidazoles | THE UPJOHN COMPANY (US) | 1976-11-16 | — | — | US | disclosed |
| US-3941803-A | 2-(Imidazol-1-yl)benzophenones | THE UPJOHN COMPANY (US) | 1976-03-02 | — | — | US | disclosed |
| US-3941802-A | 2-(Imidazol-1-yl)benzophenones | THE UPJOHN COMPANY (US) | 1976-03-02 | — | — | US | disclosed |