Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27991953 | 0.83 | S1PR1 (0.35) | S1PR1S1PR3S1PR5LTA4HGBA1 | |
| SCHEMBL27977767 | 0.78 | GBA1 (0.35) | S1PR1S1PR3S1PR5LTA4HGBA1 | |
| SCHEMBL27977764 | 0.78 | HRH3 (0.33) | S1PR1S1PR3S1PR5LTA4H | |
| SCHEMBL27991957 | 0.74 | LTA4H (0.41) | S1PR1S1PR3S1PR5LTA4HGBA1 | |
| SCHEMBL11404681 | 0.74 | S1PR1 (0.51) | S1PR1S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL27764732 | 0.73 | S1PR1 (0.50) | S1PR1S1PR3S1PR5 | |
| SCHEMBL8557666 | 0.73 | S1PR1 (0.41) | S1PR1S1PR3S1PR5GBA1 | |
| SCHEMBL27977819 | 0.73 | SMN1; SMN2 (0.32) | S1PR1S1PR3S1PR5 | |
| SCHEMBL27978043 | 0.72 | S1PR1 (0.46) | S1PR1S1PR3S1PR5 | |
| SCHEMBL27789862 | 0.71 | CYP2C19 (0.32) | GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4027028-A | HYPOTENSIVE AGENTS | SCIENCE UNION ET CIE (FR) | 1977-05-31 | — | — | US | disclosed |