Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trolamine SCHEMBL10870469 | 1.00 | MAPT (0.36) | MAPTKDM4EALOX15SMN1; SMN2 | |
| Trolamine SCHEMBL17969451 | 1.00 | MAPT (0.36) | MAPTKDM4EALOX15SMN1; SMN2 | |
| Trolamine SCHEMBL11747940 | 0.94 | MAPT (0.36) | MAPTKDM4EALOX15SMN1; SMN2 | |
| Trolamine SCHEMBL8884366 | 0.88 | MAPT (0.39) | MAPTKDM4EALOX15SMN1; SMN2 | |
| Trolamine SCHEMBL318178 | 0.88 | MAPT (0.39) | MAPTKDM4EALOX15SMN1; SMN2 | |
| Trolamine SCHEMBL27412368 | 0.88 | MAPT (0.39) | MAPTKDM4EALOX15SMN1; SMN2 | |
| Trolamine SCHEMBL7796775 | 0.88 | MAPT (0.39) | MAPTKDM4EALOX15SMN1; SMN2 | |
| Trolamine SCHEMBL5874691 | 0.88 | MAPT (0.39) | MAPTKDM4EALOX15SMN1; SMN2 | |
| Trolamine SCHEMBL22288216 | 0.85 | MAPT (0.37) | MAPTKDM4EALOX15SMN1; SMN2 | |
| Trolamine SCHEMBL7564590 | 0.85 | MAPT (0.37) | MAPTKDM4EALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4011310-A | DENTAL PROPHYLAXIS CONTAINING ALKYLAMINE FLUOROPHOSPHATES | CARTER-WALLACE, INC. (US) | 1977-03-08 | — | — | US | claimed |