Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | GJA1 | P17302 | 1/20 | 0.53 |
| ▸ | GJB2 | P29033 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | LRAT | O95237 | 2/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11776786 | 1.00 | LMNA (0.55) | LMNATSHRMEN1GJA1GJB2 | |
| SCHEMBL11780774 | 0.89 | LMNA (0.57) | LMNATSHRMEN1GJA1GJB2 | |
| SCHEMBL11780761 | 0.89 | LMNA (0.57) | LMNATSHRMEN1GJA1GJB2 | |
| SCHEMBL4439467 | 0.89 | LMNA (0.57) | LMNATSHRMEN1GJA1GJB2 | |
| SCHEMBL11775686 | 0.89 | LMNA (0.57) | LMNATSHRMEN1GJA1GJB2 | |
| SCHEMBL11775698 | 0.89 | LMNA (0.57) | LMNATSHRMEN1GJA1GJB2 | |
| SCHEMBL1389240 | 0.85 | MEN1 (0.50) | LMNATSHRMEN1GJA1GJB2 | |
| SCHEMBL2139671 | 0.85 | MEN1 (0.50) | LMNATSHRMEN1GJA1GJB2 | |
| SCHEMBL2139680 | 0.85 | MEN1 (0.50) | LMNATSHRMEN1GJA1GJB2 | |
| SCHEMBL3188633 | 0.85 | MEN1 (0.50) | LMNATSHRMEN1GJA1GJB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3965089-A | Process for the production of a cyclic ureido-derivative of a deoxystreptamine-containing antibiotic and products thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) | 1976-06-22 | — | — | US | disclosed |