Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | LRAT | O95237 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GJA1 | P17302 | 1/20 | 0.49 |
| ▸ | GJB2 | P29033 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11775686 | 1.00 | LMNA (0.57) | LMNAKDM4EALOX15LRATMEN1 | |
| SCHEMBL11780774 | 1.00 | LMNA (0.57) | LMNAKDM4EALOX15LRATMEN1 | |
| SCHEMBL11780761 | 1.00 | LMNA (0.57) | LMNAKDM4EALOX15LRATMEN1 | |
| SCHEMBL11775698 | 1.00 | LMNA (0.57) | LMNAKDM4EALOX15LRATMEN1 | |
| SCHEMBL11776786 | 0.89 | LMNA (0.55) | LMNAKDM4EALOX15LRATMEN1 | |
| SCHEMBL11776790 | 0.89 | LMNA (0.55) | LMNAKDM4EALOX15LRATMEN1 | |
| SCHEMBL25733220 | 0.80 | LRAT (0.68) | LMNAKDM4EALOX15LRATMEN1 | |
| SCHEMBL25733227 | 0.80 | LRAT (0.68) | LMNAKDM4EALOX15LRATMEN1 | |
| SCHEMBL21454660 | 0.80 | LRAT (0.68) | LMNAKDM4EALOX15LRATMEN1 | |
| SCHEMBL29885022 | 0.78 | LMNA (0.70) | LMNAKDM4EALOX15LRATMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121714-A1 | AMINOGLYCOSIDE ANTIBIOTICS TARGETING BACTERIAL 16S RIBOSOMAL RNA | Eidgenössische Technische Hochschule Zürich (CH) | 2009-11-25 | — | — | EP | claimed |
| WO-2008092690-A1 | AMINOGLYCOSIDE ANTIBIOTICS TARGETING BACTERIAL 16S RIBOSOMAL RNA | EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZÜRICH (CH) | 2008-08-07 | — | — | WO | claimed |
| EP-2121714-A1 | AMINOGLYCOSIDE ANTIBIOTICS TARGETING BACTERIAL 16S RIBOSOMAL RNA | Eidgenössische Technische Hochschule Zürich (CH) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008092690-A1 | AMINOGLYCOSIDE ANTIBIOTICS TARGETING BACTERIAL 16S RIBOSOMAL RNA | EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZÜRICH (CH) | 2008-08-07 | — | — | WO | disclosed |
| US-3965089-A | Process for the production of a cyclic ureido-derivative of a deoxystreptamine-containing antibiotic and products thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) | 1976-06-22 | — | — | US | disclosed |