Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.81 |
| ▸ | IMPDH2 | P12268 | 7/20 | 0.75 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.75 |
| ▸ | TGM2 | P21980 | 1/20 | 0.75 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.71 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.71 |
| ▸ | KRAS | P01116 | 6/20 | 0.68 |
| ▸ | CA5A | P35218 | 1/20 | 0.67 |
| ▸ | HINT1 | P49773 | 1/20 | 0.67 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.67 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.65 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.65 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.65 |
| ▸ | LDHA | P00338 | 1/20 | 0.65 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.65 |
| ▸ | FBP1 | P09467 | 1/20 | 0.65 |
| ▸ | SRC | P12931 | 1/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.65 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.65 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| E626 SCHEMBL9980018 | 0.99 | NT5E (0.83) | NT5EIMPDH2IMPDH1TGM2TAS1R3 | |
| E626 SCHEMBL18759049 | 0.99 | NT5E (0.83) | NT5EIMPDH2IMPDH1TGM2TAS1R3 | |
| E626 SCHEMBL5854 | 0.99 | NT5E (0.83) | NT5EIMPDH2IMPDH1TGM2TAS1R3 | |
| E626 SCHEMBL18785103 | 0.99 | NT5E (0.83) | NT5EIMPDH2IMPDH1TGM2TAS1R3 | |
| E626 SCHEMBL20277596 | 0.99 | NT5E (0.83) | NT5EIMPDH2IMPDH1TGM2TAS1R3 | |
| E626 SCHEMBL18763818 | 0.99 | NT5E (0.83) | NT5EIMPDH2IMPDH1TGM2TAS1R3 | |
| E626 SCHEMBL21163348 | 0.99 | NT5E (0.83) | NT5EIMPDH2IMPDH1TGM2TAS1R3 | |
| E626 SCHEMBL21803790 | 0.99 | NT5E (0.83) | NT5EIMPDH2IMPDH1TGM2TAS1R3 | |
| E626 SCHEMBL20677331 | 0.99 | NT5E (0.83) | NT5EIMPDH2IMPDH1TGM2TAS1R3 | |
| E626 SCHEMBL165027 | 0.99 | NT5E (0.83) | NT5EIMPDH2IMPDH1TGM2TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3937809-A | ADDITION COMPOUND OF A NUCLEOTIDE AND AN AMINO ACID AND THE USE THEREOF IN PROTECTION AGAINST ACTINIC RADIATION | KOLMAR LABORATORIES, INC. (US) | 1976-02-10 | — | — | US | disclosed |