Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.83 |
| ▸ | IMPDH2 | P12268 | 7/20 | 0.76 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.76 |
| ▸ | TGM2 | P21980 | 1/20 | 0.76 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.73 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.73 |
| ▸ | KRAS | P01116 | 6/20 | 0.69 |
| ▸ | CA5A | P35218 | 1/20 | 0.68 |
| ▸ | HINT1 | P49773 | 1/20 | 0.68 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.68 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.66 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.66 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.66 |
| ▸ | LDHA | P00338 | 1/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.66 |
| ▸ | FBP1 | P09467 | 1/20 | 0.66 |
| ▸ | SRC | P12931 | 1/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.66 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.66 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| E626 SCHEMBL5854 | 1.00 | NT5E (0.83) | NT5EIMPDH2IMPDH1TGM2TAS1R3 | |
| E626 SCHEMBL18785103 | 1.00 | NT5E (0.83) | NT5EIMPDH2IMPDH1TGM2TAS1R3 | |
| E626 SCHEMBL20276926 | 1.00 | NT5E (0.83) | NT5EIMPDH2IMPDH1TGM2TAS1R3 | |
| E626 SCHEMBL18759049 | 1.00 | NT5E (0.83) | NT5EIMPDH2IMPDH1TGM2TAS1R3 | |
| E626 SCHEMBL9980018 | 1.00 | NT5E (0.83) | NT5EIMPDH2IMPDH1TGM2TAS1R3 | |
| E626 SCHEMBL18763818 | 1.00 | NT5E (0.83) | NT5EIMPDH2IMPDH1TGM2TAS1R3 | |
| E626 SCHEMBL13497991 | 1.00 | NT5E (0.83) | NT5EIMPDH2IMPDH1TGM2TAS1R3 | |
| E626 SCHEMBL20677331 | 1.00 | NT5E (0.83) | NT5EIMPDH2IMPDH1TGM2TAS1R3 | |
| E626 SCHEMBL21803790 | 1.00 | NT5E (0.83) | NT5EIMPDH2IMPDH1TGM2TAS1R3 | |
| E626 SCHEMBL20277596 | 1.00 | NT5E (0.83) | NT5EIMPDH2IMPDH1TGM2TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240229109-A1 | METHODS FOR IDENTIFICATION AND RATIO DETERMINATION OF RNA SPECIES IN MULTIVALENT RNA COMPOSITIONS | MODERNATX, INC. (US) | 2024-07-11 | — | — | US | disclosed |
| US-20230233475-A1 | LIPID NANOPARTICLES CONTAINING POLYNUCLEOTIDES ENCODING GLUCOSE-6-PHOSPHATASE AND USES THEREOF | ARES CAPITAL CORPORATION, AS AGENT | 2023-07-27 | — | — | US | disclosed |
| US-20230235298-A1 | PHENYLALANINE HYDROXYLASE VARIANTS AND USES THEREOF | ARES CAPITAL CORPORATION, AS AGENT | 2023-07-27 | — | — | US | disclosed |
| US-20190211368-A1 | TRINUCLEOTIDE MRNA CAP ANALOGS | MODERNATX, INC. | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233475-A1 | LIPID NANOPARTICLES CONTAINING POLYNUCLEOTIDES ENCODING GLUCOSE-6-PHOSPHATASE AND USES THEREOF | G6PC1, GNPDA1, GPI | NT5E 752/4885IMPDH2 1116/4885IMPDH1 648/4885 |
| US-20190211368-A1 | TRINUCLEOTIDE MRNA CAP ANALOGS | RNGTT, RNMT, CPSF7 | NT5E 375/4885IMPDH2 1061/4885IMPDH1 957/4885 |
| US-20230235298-A1 | PHENYLALANINE HYDROXYLASE VARIANTS AND USES THEREOF | PAH, FARSA, P4HA1 | NT5E 1860/4885IMPDH2 300/4885IMPDH1 221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.