Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 8/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11814050 | 0.85 | MAPK14 (0.41) | MAPK14RAB9ANPC1SPRHPGD | |
| SCHEMBL11847158 | 0.76 | MAPK14 (0.39) | MAPK14RAB9ANPC1SPRHPGD | |
| SCHEMBL11863573 | 0.74 | MAPK14 (0.43) | MAPK14RAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL11775302 | 0.73 | CYP19A1 (0.46) | MAPK14RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL7471841 | 0.71 | MAPK14 (0.44) | MAPK14RAB9ANPC1SMN1; SMN2HSP90AA1 | |
| SCHEMBL11776854 | 0.71 | ALDH1A1 (0.54) | RAB9ANPC1HPGDSMN1; SMN2HSP90AA1 | |
| SCHEMBL11820065 | 0.71 | MAPK13 (0.42) | MAPK14MAPTTP53 | |
| SCHEMBL11775812 | 0.71 | HPGD (0.40) | MAPK14HPGDALDH1A1MAPTTP53 | |
| SCHEMBL11810248 | 0.69 | PDE4A (0.42) | MAPK14RAB9ANPC1SPRHPGD | |
| SCHEMBL11777810 | 0.69 | MYC (0.49) | MAPK14HSP90AA1ALDH1A1ATMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3992400-A | 1-(α-Phenyl-o-tolyl)imidazoles | THE UPJOHN COMPANY (US) | 1976-11-16 | — | — | US | disclosed |
| US-3941803-A | 2-(Imidazol-1-yl)benzophenones | THE UPJOHN COMPANY (US) | 1976-03-02 | — | — | US | disclosed |
| US-3941802-A | 2-(Imidazol-1-yl)benzophenones | THE UPJOHN COMPANY (US) | 1976-03-02 | — | — | US | disclosed |