Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 4/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 7/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11781753 | 0.91 | CISD1 (0.41) | CISD1ALDH1A1CA12CA1CA2 | |
| SCHEMBL11778816 | 0.90 | CISD1 (0.48) | CISD1ALDH1A1CA12CA1CA2 | |
| SCHEMBL11777207 | 0.81 | SIRT2 (0.39) | CISD1ALDH1A1APPFABP4FABP5 | |
| SCHEMBL11780949 | 0.80 | CISD1 (0.46) | CISD1ALDH1A1CA12CA1CA2 | |
| SCHEMBL11802842 | 0.75 | CISD1 (0.47) | CISD1ALDH1A1CA12CA1CA2 | |
| Aniline SCHEMBL11799081 | 0.74 | CISD1 (0.53) | CISD1ALDH1A1CA12CA1CA2 | |
| SCHEMBL22515417 | 0.73 | CISD1 (0.73) | CISD1ALDH1A1CA12CA1CA2 | |
| SCHEMBL11823275 | 0.73 | CISD1 (0.57) | CISD1ALDH1A1CA12CA1CA2 | |
| SCHEMBL11820413 | 0.73 | CISD1 (0.45) | CISD1ALDH1A1CA12CA1CA2 | |
| SCHEMBL11844344 | 0.72 | CISD1 (0.41) | CISD1ALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933906-A | DIURETIC | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |